The invention on hand provides a novel method rendering it possible to measure all steps of the fibrinolysis reaction, especially the dissolution of fibrin strain. Conventional microtiter plates containing micro thrombi are used in this novel clot lysis assay. Lysis is determined based on the regressing turbidity of the thrombus. Thereby, several different thrombolytic agents can be compared with each other. Both exogenic stimulation of plasmatic thrombolysis and intrinsic plasmatic thrombolysis of plasminogen activators can be measured. Experiments hitherto carried out with the novel clot lysis assay clearly indicate that different thrombolytic agents lead zu different clinical results, which most likely depend on endogenous thrombi.
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