Features: Specific implementation in the vascular system, high capacity for the incorporation of foreign DNA, not toxic to patients, high transfer efficiency, easy to handle. Tumourigenic processes and the formation of metastases crucially depend on angiogenesis. Angiogenesis in tumour tissue is stimulated, among other things, by tumour-specific factors. Among them are growth factors, such as the 'Fibroblast Growth Factor' (FGF) and the 'Vascular Endothelial Growth Factor' (VEGF). For some time, therapy concepts have been under development which are aimed specifically at the prevention of the vascular supply of tumours. A newer strategy is the specific interference with the structure and function of the tumour endothelium in order to prevent the blood supply of the tumour in the end. Herein, gene transfer systems play an important role. With them, the targeted expression of certain proteins in the tumour endothelium via specific targeting or, in contrast, specifically regulated expression becomes possible.
email@example.com | TechnologieAllianz e.V.
Dosing system of bulk material (granulates) for expansion injection molding
19.01.2017 | TechnologieAllianz e.V.
Efficient method for Chain Multiplication of unsaturated fatty acids - synthesis of ultra long-chain compounds
18.01.2017 | TechnologieAllianz e.V.
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
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