New Active Agents for Therapy, Diagnostics and Prophylaxis of Alzheimer and TSE-related Diseases
The invention relates to a new chemical class of compounds, which modulate the aggregation of amyloidogenetic proteins or peptides. The heterocylic or aromatic active compounds, with the general structure as shown in the figure above, are able to form a complex with amyloidogenetic proteins or peptides according to the donor-acceptor-donor pattern, leading to inhibition of the amyloid aggregation.
Next to the compounds and the use of the compounds, the invention also covers a proprietary method for the synthesis of the compounds.
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