Presentation of HPV L2 Epitopes by using thioredoxin scaffold
The current invention provides a prophylactic HPV vaccine. Immunization against peptides from the HPV L2 protein gives a robust immune reaction that provides cross-protection against a variety of other high-risk HPV strains. Tha vaccine is based on a thioredoxin-L2 construct and can be produced in standard E. coli bacteria, which makes a cost-effective production feasible.
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DKFZ (German Cancer Research Center, Deutsches Krebsforschungszentrum)
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