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Poly mutant MAPT-gene variant for the generation of human Tauopathies ex vivo and for the identification of new therapeutic options for the treatment

04.07.2013

The microtubule associated tau-protein in its hyper-phosphorylated form is a key element in diseases of the nervous system, the so- called tauopathies. We offer a neuronal model system with an missfolded Tau protein that is based on a poly-mutant MAPT-gene variant.

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