Optical Tomography (OT), SPECT and CT combinations for preclinical imaging
Optical fluorescence and gammalabeled radiopharmaceutical imaging offer complementary ways of probing and assessing the physiology of small animals. With the increasing use of both methods for functional molecular imaging in small animal models for applications such as cancer research and drug development, it has become more important to integrate their results, particularly for studies of the same animal. This can be performed through image registration of separate studies or through simultaneous tomographic acquisition with implicit registration of the two imaging modalities.
DKFZ developed an optical imaging detector for fluorescence and bioluminescence in small animal imaging, which is compatible for single-photon emission computed tomography (SPECT).
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DKFZ (German Cancer Research Center, Deutsches Krebsforschungszentrum)
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