The invention relates to a novel class of analgesics, as well as their therapeutic utilization and their method of synthe-sis. The novel class of amino-, imino-1,2,3-triazine derivatives presented is classified as non-opioid analgesics and may be used for the treatment and relief of all kinds of pain-related diseases.
The compounds’ positive analgesic effect has been successfully proven in a mice pain model and is based upon their advantageous agonizing of potas-sium channels.
Compounds of the invention can be produced and applied in all commonly used galenic formulations (solid and liquid), ranging from tablets and film-coated tablets, over capsules, powders, granulates and pills, to solutions and sprays.
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Dr. Markus Kähler, Dr. Stefanie Klingelhöfer, Karl-Heinz Rehfeldt, Astrid Stichnoth
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