Novel cyclodextrins for hydrophobic drug delivery

Scientists of Saarland University and Julius Maximilian University of Würzburg have developed novel water soluble 6-thioalkyl-cyclodextrins, which form highly stable complexes with APIs. The new cyclodextrins show low ion strength in solution and no pH dependence. They can be obtained in well-defined stoichiometry, no statistic, randomly substituted products are generated, thereby simplifying quality control and analysis. Even highly volatile substances such as the anesthetics halothane or sevoflurane can be complexed. For example, one of the new 6-thioalkyl-cyclodextrins showed the highest binding affinities sevoflurane and halothane, much higher than native cyclodextrins or and known cyclodextrin derivatives.

Further information: PDF

Universität des Saarlandes Wissens- und Technologietransfer GmbH PatentVerwertungsAgentur der saarländischen Hochschulen
Phone: +49 (0)681/302-71302

Contact
Dr. Conny Clausen, Dr. Nicole Comtesse, Dr. Frank Döbrich, Dr. Miriam Kranz, Dr. Christof Schäfer

As Germany's association of technology- and patenttransfer agencies TechnologieAllianz e.V. is offering businesses access to the entire range of innovative research results of almost all German universities and numerous non-university research institutions. More than 2000 technology offers of 14 branches are beeing made accessable to businesses in order to assure your advance on the market. At www.technologieallianz.de a free, fast and non-bureaucratic access to all further offers of the German research landscape is offered to our members aiming to sucessfully transfer technologies.

Media Contact

info@technologieallianz.de TechnologieAllianz e.V.

All latest news from the category: Technology Offerings

Back to home

Comments (0)

Write a comment

Newest articles

Lighting up the future

New multidisciplinary research from the University of St Andrews could lead to more efficient televisions, computer screens and lighting. Researchers at the Organic Semiconductor Centre in the School of Physics and…

Researchers crack sugarcane’s complex genetic code

Sweet success: Scientists created a highly accurate reference genome for one of the most important modern crops and found a rare example of how genes confer disease resistance in plants….

Evolution of the most powerful ocean current on Earth

The Antarctic Circumpolar Current plays an important part in global overturning circulation, the exchange of heat and CO2 between the ocean and atmosphere, and the stability of Antarctica’s ice sheets….

Partners & Sponsors