Staphylococcus aureus is a gram positive bacterium frequently occurring in nature. Over the years a resistant form developed which is known as MRSA - methicillin resistant Staphylococcus aureus. MRSA can cause severe problems especially in immune compromised patients. The antibiotic of choice to treat these infections was vancomycin. But since resistance to vancomycin has also been observed as well as the development of multiple resistances the application of the recently used antibiotics is increasingly limited. Novel active substances are provided. Their application will overcome resistance mechanisms based on genetic variability because they show a different mode of action.
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