Scientists of the University of Duisburg-Essen developed an RT-PCR based test, with a sensitivity of up to 0.005% against a background of wild type alleles, detecting deletions and insertions as well as point mutations. The assay is robust and applicable in a broad range of laboratories.
So far current methods for screening the epidermal growth factor-receptor (EGFR)-gene in patients with non-small lung cancer (NSCLC) require taking tumor biopsies. By applying this sensitive technology, it is possible to detect even one single mutated circulating tumor (CTC) cell per milliliter peripheral blood. As sequential biopsies or biopsies of multiple tumor lesions are not routinely performed due to patient safety, this opens new non-invasive possibilities for monitoring the mutation status of patients during treatment and to detect disease relapse early.
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Highly conductive pastes for printable electronic applications and devices
18.01.2017 | TechnologieAllianz e.V.
Efficient method for Chain Multiplication of unsaturated fatty acids - synthesis of ultra long-chain compounds
18.01.2017 | TechnologieAllianz e.V.
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
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