This invention describes solid-state sensors with electrical control of the affinity of chemosensitive materials. This configuration enables rapid regeneration of sensors after analyte binding and increases selectivity. The sensor has been designed as a six-electrode chemoresistor that contains four electrodes in the center for separate measurements of resistance as well as two other external electrodes to monitor the redox status of the sensor material. This object is accomplished in the format of a solid-state chemosensor.
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