Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Microstructured Polymer Stents


Stents are small tubes or tubular shaped meshes which are used to keep or rebuild the luminal size of passages in the human body like coronary arteries or the esophagus. They are most commonly used in the treatment of stenosis (narrowing of the blood vessels). Stents can be utilized as implants or in conjunction with an angioplasty (a technique for widening narrowed arteries). One of the most common complications when using stents is in-stent restenosis and stent loss. In-stent restenosis is the renarrowing of the implanted stent which occurs in ~ 30 % of all cases.<br><br> To prevent restenosis drug eluting stents have been developed. This has been a success to a certain extent, but a big problem of drug eluting stents are the late effects, such as increased risk of bleeding, acute intoxication and the formation of tumors <br><br> <strong>Technology</strong><br> This novel microstructured polymer stents are made of a shape memory polymer (e.g. polyurethane). Below body temperature the shape memory polymer stent has a compressed geometry (temporary form, see left figure). When heating the shape memory polymer stent on body temperature the stent turns into an uncompressed geometry (predefined permanent form, see right figure). <br><br>

The inner surface of the stent is microstructured limiting laminar flows and preventing in-stent restenosis. The outer surface is structured (e.g. microporous) leading to a fixation of the stent preventing stent loss. Therefore the polymer stent is a reliable device for angioplasty procedures.<br><br> The structuring of the polymer surface can be achieved with different meth-ods e.g. via moulding, laser structuring or etching. <br><br> <strong>Benefits</strong><br> <ul> <li>Prevention of restenosis and stent loss</li> <li>Prevention of long-term effects</li> </ul><br> <strong>IP Rights</strong><br> DE application (11/2008)<br><br> <strong>Origin</strong><br> Technische Universität Berlin</p>

Further Information: PDF

ipal GmbH
Phone: +49 (0)30/2125-4820

Dr. Dirk Dantz | TechnologieAllianz e.V.
Further information:

More articles from Technology Offerings:

nachricht Highly active and selective ligands for Integrin &#945;vß6
13.10.2015 | TechnologieAllianz e.V.

nachricht Improved ex-vivo expansion of immune cells for use in cell therapy
17.11.2015 | TechnologieAllianz e.V.

All articles from Technology Offerings >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Climate study finds evidence of global shift in the 1980s

Planet Earth experienced a global climate shift in the late 1980s on an unprecedented scale, fuelled by anthropogenic warming and a volcanic eruption, according to new research published this week.

Scientists say that a major step change, or ‘regime shift’, in the Earth’s biophysical systems, from the upper atmosphere to the depths of the ocean and from...

Im Focus: Innovative Photovoltaics – from the Lab to the Façade

Fraunhofer ISE Demonstrates New Cell and Module Technologies on its Outer Building Façade

The Fraunhofer Institute for Solar Energy Systems ISE has installed 70 photovoltaic modules on the outer façade of one of its lab buildings. The modules were...

Im Focus: Lactate for Brain Energy

Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.

In comparison to other organs, the human brain has the highest energy requirements. The supply of energy for nerve cells and the particular role of lactic acid...

Im Focus: Laser process simulation available as app for first time

In laser material processing, the simulation of processes has made great strides over the past few years. Today, the software can predict relatively well what will happen on the workpiece. Unfortunately, it is also highly complex and requires a lot of computing time. Thanks to clever simplification, experts from Fraunhofer ILT are now able to offer the first-ever simulation software that calculates processes in real time and also runs on tablet computers and smartphones. The fast software enables users to do without expensive experiments and to find optimum process parameters even more effectively.

Before now, the reliable simulation of laser processes was a job for experts. Armed with sophisticated software packages and after many hours on computer...

Im Focus: Quantum Simulation: A Better Understanding of Magnetism

Heidelberg physicists use ultracold atoms to imitate the behaviour of electrons in a solid

Researchers at Heidelberg University have devised a new way to study the phenomenon of magnetism. Using ultracold atoms at near absolute zero, they prepared a...

All Focus news of the innovation-report >>>



Event News

Fraunhofer’s Urban Futures Conference: 2 days in the city of the future

25.11.2015 | Event News

Gluten oder nicht Gluten? Überempfindlichkeit auf Weizen kann unterschiedliche Ursachen haben

17.11.2015 | Event News

Art Collection Deutsche Börse zeigt Ausstellung „Traces of Disorder“

21.10.2015 | Event News

Latest News

Antibody-Drug Compounds and Immunotherapy to Treat Breast Cancer

26.11.2015 | Life Sciences

Get to the point with electric cars

26.11.2015 | Power and Electrical Engineering

Climate study finds evidence of global shift in the 1980s

26.11.2015 | Studies and Analyses

More VideoLinks >>>