Method for the determination of the concentration of asymmetric dimethylarginine
Elevated plasma levels of ADMA are described for a number of diseases as hypertension, hypercholesterolemia, renal insufficiency or diabetes mellitus. The invention provides a method for the simultaneous determination of the concentration of asymmetric dimethylarginine (ADMA), arginine and symmetric dimethylarginine (SDMA) in biological probes using chromatography combined with tandem mass spectrometry.
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