Method for the Detection of Dysfunctional High Density Lipoprotein (HDL) prior to the administration of HDL raising drugs
The invention describes a new method for the detection of dysfunctional High Density Lipoprotein (HDL) prior to the administration of HDL raising drugs. HDL from patients with mild to severe CKD, is specifically associated with a component of human blood plasma which alters the endothelial effects of HDL. This novel pathomechanism leads to a HDL phenotype promoting hypertension and likely accelerating atherosclerosis even in incipient CKD that may contribute to elevated cardiovascular morbidity and mortality.
Further Information: PDF
Universität des Saarlandes Wissens- und Technologietransfer GmbH PatentVerwertungsAgentur der saarländischen Hochschulen
Phone: +49 (0)681/302-71302
Contact
Dipl.-Kfm. Axel Koch (MBA), Dr. Conny Clausen, Dr. Nicole Comtesse, Dr. Frank Döbrich
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Machine learning algorithm reveals long-theorized glass phase in crystal
Scientists have found evidence of an elusive, glassy phase of matter that emerges when a crystal’s perfect internal pattern is disrupted. X-ray technology and machine learning converge to shed light…
Mapping plant functional diversity from space
HKU ecologists revolutionize ecosystem monitoring with novel field-satellite integration. An international team of researchers, led by Professor Jin WU from the School of Biological Sciences at The University of Hong…
Inverters with constant full load capability
…enable an increase in the performance of electric drives. Overheating components significantly limit the performance of drivetrains in electric vehicles. Inverters in particular are subject to a high thermal load,…
