In situ-forminghydrogelsbased onDiels-Alder reactions

The present invention relates to the preparation of in situ-forming hydrogels by cross-linking macromonomers using the Diels-Alder reaction. Hydrophilic macromolecules are functionalized with dienes and dienophiles; the number of functionalities is at least two per macromonomer. The macromonomers are cross-linked in aqueous solutions outside or inside the human body by a [4+2] cycloaddition reaction to form highly elastic hydrogels. The hydrogels can be used as biomaterials for biomedical applications, as scaffolds for living cells, or as delivery system for the controlled release of proteins.

Further information: PDF

Bayerische Patentallianz GmbH
Phone: +49 89 5480177-0

Contact
Peer Biskup

As Germany's association of technology- and patenttransfer agencies TechnologieAllianz e.V. is offering businesses access to the entire range of innovative research results of almost all German universities and numerous non-university research institutions. More than 2000 technology offers of 14 branches are beeing made accessable to businesses in order to assure your advance on the market. At www.technologieallianz.de a free, fast and non-bureaucratic access to all further offers of the German research landscape is offered to our members aiming to sucessfully transfer technologies.