New Enzyme Anhydrofructose-Reductase
The invention affects the novel bacterial enzyme 1,5-anhydro-D-fructose-reductase. In a regio- and stereoselective reaction 1,5-anhydro-D-fructose (AF) is quantitatively reduced to 1,5-anhydro-D-mannitol. Generally AF occurs naturally in connection with the enzymatic degradation of storage poly-saccharides like starch or glycogen and the further eucaryotic metabolism results in the sugar polyol 1,5-anhydro-D-glucitol (so-called Third Gly-cogenolytic Pathway). The bacterial, NADPH-dependent enzyme exhibits a limited substrate spectrum and reduces other structure analogous 2-keto-aldoses. Due to the heterologous expression in E. coli the biocatalyst is available in sufficient amounts. The specific analysis of AF and selective synthesis of the manno-configurated reduction products are counted among the most important areas of application of the new AF-reductase.
Further Information: PDF
Universität des Saarlandes Wissens- und Technologietransfer GmbH PatentVerwertungsAgentur der saarländischen Hochschulen
Phone: +49 (0)681/302-6340
Contact
Dip. Chem. Dagmar Vössing, Dipl.-Kfm. Axel Koch MBA, Dipl. Ing. Gerd Schneider
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Bringing bio-inspired robots to life
Nebraska researcher Eric Markvicka gets NSF CAREER Award to pursue manufacture of novel materials for soft robotics and stretchable electronics. Engineers are increasingly eager to develop robots that mimic the…
Bella moths use poison to attract mates
Scientists are closer to finding out how. Pyrrolizidine alkaloids are as bitter and toxic as they are hard to pronounce. They’re produced by several different types of plants and are…
AI tool creates ‘synthetic’ images of cells
…for enhanced microscopy analysis. Observing individual cells through microscopes can reveal a range of important cell biological phenomena that frequently play a role in human diseases, but the process of…
