Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Discrimination of enantiomers by means of broadband femtosecond-circular dichroism-laser ionization mass spectrometry (CD-LIMS)

23.06.2009
The invention at hand provides for the first time a combination of broadband circularly polarized femtosecond laser radiation with laser ionization mass spectrometry (LIMS) in a circular dichroic application.<p>

The enantiomer-specific light-matter interaction is used directly for ionization, so that a separation of substance mixtures is no longer required. Hereby, circularly polarized femtosecond laser pulses are applied whose central wavelength is in the range of 200 nm to 1100 nm and whose bandwidth is very large. In the limit of a very broad white-light continuum, the fs laser pulse intrinsically contains the wavelengths which are suitable for the respective molecule. The chemical sample to be analyzed is ionized by means of this broad-band laser radiation and analyzed by mass spectrometry immediately afterwards. The chemical substance to be analyzed can be a single chemical substance or a mixture of several chemical substances, respectively, wherein any substance contained in the sample can be enantiomerically pure, or present in the form of an enantiomeric mixture.<p> The femtosecond laser pulse used in the device and the method according to the present invention ensures the intensity which is required for the ionization and fragmentation of the substances to be analyzed. During irradiation with the femtosecond laser pulse, it is constantly switching between RCPL and LPCL. i.e. between right-circularly and left-circularly polarized light, and the respective ion yield is measured.<p>

Furthermore, the inventors have developed software for the analysis of the obtained data.

Further Information: PDF

TransMIT Gesellschaft für Technologietransfer mbH
Phone: +49 (0)641/943 64-12

Contact
Dr. Peter Stumpf

info@technologieallianz.de | TechnologieAllianz e.V.
Further information:
http://www.technologieallianz.de/angebote.php?sort=sag&id=1619&lang=en
http://www.technologieallianz.de

More articles from Technology Offerings:

nachricht High-throughput screening system for directed evolution experiments using novel compartments
08.12.2016 | TechnologieAllianz e.V.

nachricht Novel CVD-based growth process for zinc oxide layers
08.12.2016 | TechnologieAllianz e.V.

All articles from Technology Offerings >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electron highway inside crystal

Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.

Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

09.12.2016 | Life Sciences

Scientists produce a new roadmap for guiding development & conservation in the Amazon

09.12.2016 | Ecology, The Environment and Conservation

Satellites, airport visibility readings shed light on troops' exposure to air pollution

09.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>