The invention provides a multi-layer bio-nano-coating to optimise the adhesion of gingival fibroblasts to the implant. This bio-nano-coating is tightly connected to the implant and at the same time ensures flexibility of the molecular layers. Further the bio-nano-coating enables the native conformation of embedded molecules, e.g. of fibronectin. This is essential to attract gingival fibroblasts, which then link the gingiva to the titan surface of the implant by generating their own extra-cellular matrix.
In summary, the invention comprises medicinal implants with biofunctional coating, which will greatly reduce the incidence of peri-implantitis and other complications related to the insufficient adhesion of the tissue to the implant.
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Dipl.-Ing. Alfred Schillert
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