While the need for detailed quantitative information about fatty acid metabolism from all available model systems, such as purified proteins, cultivated cell lines, primary cells, isolated organs and whole organisms is steadily increasing, we face a concomitant decrease of the accessibility and acceptance of a major technology used to obtain these data in the last 60 years, namely the use of radiolabeled fatty acids for monitoring fatty acid metabolism because of the related costs and safety concerns. Another drawback is the limited sensitivity of experiments using radioactive fatty acids. The relevant isotopes, 3H and 14C, have moderate or low specific activities and require long exposure times in order to obtain a meaningful result.
firstname.lastname@example.org | TechnologieAllianz e.V.
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