Commercial Opportunities CHK1- and CHK2-SNPs have been well validated. Genotyping of these SNPs will allow identifying responders and non-responders under therapy with CHK-inhibitors and other anti-cancer drugs. Besides the pre-estimation of the efficacy of pharmacological therapies, dose adjustments of non-pharmacological therapies like irradiation should be possible. Genetic association studies have clearly demonstrated significant effects of CHK1- and CHK2-SNPs upon the outcome in different haematological and solid cancers. For example, excellent correlations with the progression of CLL, bladder, colorectal carcinoma and glioblastoma have been observed. The prognostic value will also be given for other cancer entities. Since the biological function of the CHK1 and CHK2 are well known and characterized, corresponding diagnostic tests will be widely accepted.
firstname.lastname@example.org | TechnologieAllianz e.V.
Dosing system of bulk material (granulates) for expansion injection molding
19.01.2017 | TechnologieAllianz e.V.
Efficient method for Chain Multiplication of unsaturated fatty acids - synthesis of ultra long-chain compounds
18.01.2017 | TechnologieAllianz e.V.
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
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