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Catheter for treatment of preterm premature rupture of membranes

Preterm premature rupture of membranes (PPROM) is one of the leading causes of perinatal morbidity and mortality. It complicates 3% of pregnancies and is responsible for a third of all preterm births. Repetitive transabdominal amnioinfusions for treatment of PPROM showed low benefit in case of fluid loss within 6h. The successful treatment of PPROM by the use of a subcutaneously implanted Amniotic Fluid Replacement Port System in humans for long-term amnioinfusion was approved twice in patents. In addition, the new technology is improved by a special intrauterine catheter which is characterized by a small diameter and can be placed via a very thin finder needle under ultrasound control. The catheter is fixed by the use of two balloons, which surround the uterus’ wall. The balloons therefore avoid the dislocation of the catheter and seal the uterus’ puncture site, whereby the risk of an ascending peritonitis is decreased significantly.

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Dr. Klaus Kobek | TechnologieAllianz e.V.
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