Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Biocompatible and Bioactive Bone Substitute Material

08.10.2012
<strong>Background</strong><br>

Bone medicine and tissue engineering is becoming increasingly important in the ageing modern society. Up to 55% of over fifty year olds develop osteo-porosis or the pre-osteoporosis syndrome osteopenia. In some cases a bone replacement is required. The same applies to patients with acute and chronic osteomyelitis, both of which remain difficult to treat. <br><br> Major difficulties in bone medicine are the limited availability of autologous bone tissue for transplantation and the risk of rejection and disease transmission in the use of allografts. <br><br> <strong>Technology</strong><br>

The present invention provides a novel method for the production of a bio-compatible and bioactive bone substitute material, which is taking advantage of the foaming behavior of polymers contacted with a supercritical gas (CO2). This method allows for the in situ chemical synthesis of relevant inorganic compounds inside a polymeric matrix (e.g. PLGA or PCL) with a very adaptable composition and distribution of bioactive cations (calcium and strontium) within the bone substitute material. Furthermore, strontium acts as so called dual action bone agent - stimulating bone growth, while simultaneously inhibiting biological bone resorption processes.<br><br> This characteristic is expected to enable a much improved bone tissue growth in the synthetic matrix.<br><br> <strong>Benefits</strong> <ul> <li>Improved bone tissue growth in the synthetic matrix</li> <li>Better control of desired granularity </li> <li>More even distribution of the bioactive components in the bone sub-stitute material</li> <li>Dual action of strontium: bone growth stimulation and resorption inhibition.</li> </ul> <p><strong>IP Rights</strong><br> US patent application filed (11/2010)<br> PCT application filed (10/2011) <br> <br> <strong>Patent Owner</strong><br> Technische Universität Berlin

Further Information: PDF

ipal GmbH
Phone: +49 (0)30/2125-4820

Contact
Dr. Dirk Dantz

info@technologieallianz.de | TechnologieAllianz e.V.
Further information:
http://www.technologieallianz.de/angebote.php?sort=sag&id=2914&lang=en
http://www.technologieallianz.de

More articles from Technology Offerings:

nachricht Parenteral controlled drug delivery - polymers
10.02.2017 | TechnologieAllianz e.V.

nachricht Parenteral controlled drug delivery - oleogels
10.02.2017 | TechnologieAllianz e.V.

All articles from Technology Offerings >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Switched-on DNA

20.02.2017 | Materials Sciences

Second cause of hidden hearing loss identified

20.02.2017 | Health and Medicine

Prospect for more effective treatment of nerve pain

20.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>