Bioactive pre-tubulysins and use thereof
Pre-tubulysin was already claimed as a hypothetically common preliminary stage of tubulysins in 2004. Now it is available by synthesis and can be used for increasing the output of tubulysin production by implementing it in tubulysin producing hosts. Besides the possibility to obtain tubulysin by biotransformation of pre-tubulysin, the later shows high biological activity by itself and therefore might be useful in cancer therapy as an self-contained agent.
Further Information: PDF
Universität des Saarlandes Wissens- und Technologietransfer GmbH PatentVerwertungsAgentur der saarländischen Hochschulen
Phone: +49 (0)681/302-71302
Contact
Dipl.-Kfm. Axel Koch (MBA), Dr. Conny Clausen, Dr. Hauke Studier, Dr. Susanne Heiligenstein
Media Contact
All latest news from the category: Technology Offerings
Newest articles
“Nanostitches” enable lighter and tougher composite materials
In research that may lead to next-generation airplanes and spacecraft, MIT engineers used carbon nanotubes to prevent cracking in multilayered composites. To save on fuel and reduce aircraft emissions, engineers…
Trash to treasure
Researchers turn metal waste into catalyst for hydrogen. Scientists have found a way to transform metal waste into a highly efficient catalyst to make hydrogen from water, a discovery that…
Real-time detection of infectious disease viruses
… by searching for molecular fingerprinting. A research team consisting of Professor Kyoung-Duck Park and Taeyoung Moon and Huitae Joo, PhD candidates, from the Department of Physics at Pohang University…