Application of A-Ring-Aromatized Acetyl-Minocyclines for Therapy of T-Cell Mediated Diseases

A Pentaacetylcyclin – an A-Ring aromatized and acetylated derivative of minocycline – is provided which exhibits immunomodulatory and neuroprotective action. The compound has been applied intraperitonally and orally in the mouse model of Multiple Sclerosis EAE (Experimental Autoimmune Enzephalomyelitis. Comparably low concentrations led to a relief in the acute phase of the disease.

Further Information: PDF

ESA Patentverwertungsagentur Sachsen-Anhalt GmbH
Phone: +49 (0)391/8 10 72 20

Contact
Peter Lösler

Media Contact

info@technologieallianz.de TechnologieAllianz e.V.

All latest news from the category: Technology Offerings

Back to home

Comments (0)

Write a comment

Newest articles

Results for control of pollutants in water

Brazilian scientists tested a simple and sustainable method for monitoring and degrading a mixture of polycyclic aromatic hydrocarbons, compounds present in fossil fuels and industrial waste. An article published in the journal Catalysis…

A tandem approach for better solar cells

Perovskite-based solar cells were first proved in 2009 to have excellent light-absorbing properties of methylammonium lead bromide and methylammonium lead iodide, collectively referred to as lead halide perovskites or, more…

The behavior of ant queens is shaped by their social environment

Specialization of ant queens as mere egg-layers is reversible / Queen behavioral specialization is initiated and maintained by the presence of workers. The queens in colonies of social insects, such…

Partners & Sponsors