New animal model for sporadic Alzheimer's Disease (AD)
Alzheimer's Disease (AD) is the main neurodegenerative disease worldwide. It places a large social and financial burden on society due to the need of life-long intensive care. There are two forms of AD identified by researchers, sporadic AD (SAD) and familial autosomal dominant AD (genetic background). Sporadic AD is the more common form, accounting for 90-95% of cases. Surprisingly, there is no animal model for the sporadic AD form available on the market.
Scientists of the University of Göttingen have now developed a transgenic mouse model for sporadic Alzheimer's Disease (TBA83). This is the first mouse model without any mutations showing neurological deficits by transgenic over-expressing of a particular form of amyloid beta peptides. The neurological phenotype resembles that of mouse models with neurodegeneration. We are now looking for companies, which are interested in licensing, developing and commercializing our approach.
Further Information: PDF
MBM ScienceBridge GmbH
Phone: (0551) 30724-151
Contact
Dr. Jens-Peter Horst
Media Contact
All latest news from the category: Technology Offerings
Newest articles
“Nanostitches” enable lighter and tougher composite materials
In research that may lead to next-generation airplanes and spacecraft, MIT engineers used carbon nanotubes to prevent cracking in multilayered composites. To save on fuel and reduce aircraft emissions, engineers…
Trash to treasure
Researchers turn metal waste into catalyst for hydrogen. Scientists have found a way to transform metal waste into a highly efficient catalyst to make hydrogen from water, a discovery that…
Real-time detection of infectious disease viruses
… by searching for molecular fingerprinting. A research team consisting of Professor Kyoung-Duck Park and Taeyoung Moon and Huitae Joo, PhD candidates, from the Department of Physics at Pohang University…