It has been scientifically proven that about 15 per cent of all cancer cases are the result of viral infection, but many researchers believe that even more cancers could be caused by viruses.
Among other theories, it is suggested that the Epstein-Barr virus could be a possible cause of breast cancer and that the cytomegalovirus might cause the malignant brain tumour glioblastoma.
"There is some controversy in that we have not found any viruses in these forms of cancer, but if there were any viral involvement in breast cancer and glioblastoma, it is likely that we would have found some trace of it. We have based our research on American material, which is extremely comprehensive," says Erik Larsson, who is a researcher at the Sahlgrenska Academy at the University of Gothenburg.
The study was published in the highly-regarded scientific journal "Nature Communications". The study involved the researchers using powerful computers to conduct in-depth analysis of 700 billion DNA sequences from more than 4,000 tumours.
"We conducted an unbiased search for viruses in 19 different types of cancer. The analysis has neatly confirmed the links that are already known, which effectively confirms that we are using the right method," says Erik Larsson.
The result of the study is a massive chart of viral presence in cancer. Among other things, the study was able to confirm that liver cancer is often caused by the hepatitis virus, and that the human papilloma virus causes cervical cancer. The study also shows that viral infection also causes major adaptations in the tumour cell, and that virus-positive tumours from widely different organs can therefore display considerable similarities.
The article The landscape of viral expression and host gene fusion and adaptation in human cancer was published online on 1 October.
Erik Larsson | Source: EurekAlert!
Further information: www.gu.se
More articles from Studies and Analyses:
Promising Alzheimer´s drug trialled in a large EU study
09.12.2013 | University of Gothenburg
Majority of epilepsy surgery patients enjoy improvement in their physical and social well-being
09.12.2013 | Henry Ford Health System
In power electronics systems bonded connections create the central electrical connections between adjoining surfaces.
The quality of these bonded connections is one of the main factors that determines the reliability and availability of drive systems in electric vehicles, and hence constitutes a major design challenge for German auto manufacturers aiming to electrify their vehicles.
Now the partners participating in the RoBE (Robust Bonds in ...
International team of scientists develops new feedback method for optimizing the laser pulse shapes used in the control of chemical reactions
In many ways, traditional chemical synthesis is similar to cooking. To alter the final product, you can change the ingredients or their ratio, change the method of mixing ingredients, or change the temperature or pressure of the environment of the ingredients.
Like an accomplished chef, chemists have become very skilled ...
A genetic defect protects mice from infection with influenza viruses
A new study published in the scientific journal PLOS Pathogens points out that mice lacking a protein called Tmprss2 are no longer affected by certain flu viruses.
The discovery was made by researchers from the Helmholtz Centre for Infection Research (HZI) in Braunschweig in collaboration with colleagues from Göttingen and ...
The Light: Global study gets underway with online user survey
Light has a fundamental impact on our sense of well-being and performance. In cooperation with Zumtobel, a supplier of lighting solutions, Fraunhofer IAO has launched a global user survey of lighting quality in offices. The objective is to identify the best lighting conditions for a variety of spaces and lighting ...
Quantum entanglement, a perplexing phenomenon of quantum mechanics that Albert Einstein once referred to as “spooky action at a distance,” could be even spookier than Einstein perceived.
Physicists at the University of Washington and Stony Brook University in New York believe the phenomenon might be intrinsically linked with wormholes, hypothetical features of space-time that in popular science fiction can provide a much-faster-than-light shortcut from one part of the universe to another.
But here’s the catch: One couldn’t actually ...
09.12.2013 | Materials Sciences
09.12.2013 | Life Sciences
09.12.2013 | Studies and Analyses
05.12.2013 | Event News
04.12.2013 | Event News
12.11.2013 | Event News