In this study a team of researchers, led by Peggy Näsman, Karolinska Institute, Department of Dental Medicine, Stockholm, Sweden, investigated possible adverse health effects on bone tissue from drinking fluoridated water.
The study included a large cohort of Swedish residents chronically exposed to various fluoride levels, with the hypothesis of a possible association between fluoride level in the drinking water and the risk of hip fracture. With nearly half a million individuals participating in this study, this is believed to be one of the largest studies of its kind. The complete study is published in the OnlineFirst portion of the IADR/AADR Journal of Dental Research.
The cariostatic benefit from water fluoridation is indisputable, but there has been debate over the past 60 years on possible adverse effects from fluoride on human health. The study assessed the association between long-term (chronic) drinking water fluoride exposure and hip fracture (ICD-7-9: '820' and ICD-10: 'S72.0-S72.2') in Sweden using nationwide registers.
All individuals born in Sweden between January 1, 1900 and December 31, 1919, alive and living in their municipality of birth at the time of start of follow up were eligible for this study. The information on the eligible study subjects (n=473,277) was linked among the Swedish National In-patient Register (IPR), the Swedish Cause of Death Register, and the Register of Population and Population Changes. Estimated individual drinking water fluoride exposure was stratified into four categories: very low <0.3mg/L, low 0.3 - 0.69mg/L, medium 0.7 - 1.49mg/L and high ≥1.5mg/L.
Näsman and her team of researchers found no association between chronic fluoride exposure and the risk of hip fracture. The risk estimates did not change in analyses restricted to only low trauma osteoporotic hip fractures. This research suggests that chronic fluoride exposure from drinking water does not seem to have any important effects on the risk of hip fracture, in the investigated exposure range.
"Though research continues to prove the health benefits associated with drinking fluoridated water, the potential for health risks should continue to be studied," said IADR President Helen Whelton. "It is promising to know that this cohort study, performed in Sweden, doesn't find an association between drinking fluoridated water and hip fractures."
Visit http://jdr.sagepub.com/content/early/recent for a link to the complete article or contact Ingrid L. Thomas at firstname.lastname@example.org to request the PDF.
About the Journal of Dental Research
The IADR/AADR Journal of Dental Research is a multidisciplinary journal dedicated to the dissemination of new knowledge in all sciences relevant to dentistry and the oral cavity and associated structures in health and disease.
About the International Association for Dental Research
The International Association for Dental Research (IADR) is a nonprofit organization with more than 11,500 individual members worldwide, dedicated to: (1) advancing research and increasing knowledge for the improvement of oral health worldwide, (2) supporting and representing the oral health research community, and (3) facilitating the communication and application of research findings. To learn more, visit http://www.iadr.org. The American Association for Dental Research (AADR) is the largest Division of IADR, with more than 3,500 members in the United States. To learn more, visit http://www.aadronline.org.
Ingrid L. Thomas | Source: EurekAlert!
Further information: www.iadr.org
More articles from Studies and Analyses:
Development near Oregon, Washington public forests
04.12.2013 | USDA Forest Service - Pacific Northwest Research Station
Mammography screening intervals may affect breast cancer prognosis
04.12.2013 | Radiological Society of North America
Quantum entanglement, a perplexing phenomenon of quantum mechanics that Albert Einstein once referred to as “spooky action at a distance,” could be even spookier than Einstein perceived.
Physicists at the University of Washington and Stony Brook University in New York believe the phenomenon might be intrinsically linked with wormholes, hypothetical features of space-time that in popular science fiction can provide a much-faster-than-light shortcut from one part of the universe to another.
But here’s the catch: One couldn’t actually ...
A star is formed when a large cloud of gas and dust condenses and eventually becomes so dense that it collapses into a ball of gas, where the pressure heats the matter, creating a glowing gas ball – a star is born.
New research from the Niels Bohr Institute, among others, shows that a young, newly formed star in the Milky Way had such an explosive growth, that it was initially about 100 times brighter than it is now. The results are published in the scientific journal, Astrophysical Journal Letters.
The young ...
EPFL scientists have shown how to achieve a dramatic increase in the capacity of optical fibers; Their simple, innovative solution reduces the amount of space required between the pulses of light that transport data
Optical fibers carry data in the form of pulses of light over distances of thousands of miles at amazing speeds. They are one of the glories of modern telecommunications technology.
However, their capacity is limited, because the pulses of light need to be lined up one after the other in ...
NASA's Hurricane and Severe Storms Sentinel airborne mission known as HS3 wrapped up for the 2013 Atlantic Ocean hurricane season at the end of September, and had several highlights. HS3 will return to NASA’s Wallops Flight Facility in Wallops Island, Va., for the 2014 Atlantic hurricane season.
During the 2013 mission, two unmanned Global Hawks flew from Wallops for the first time. The mission highlights included studying the Saharan Air Layer, following the genesis of a tropical storm, finding a unique hybrid core or center circulation in a redeveloped storm, obtaining measurements on the strongest side of ...
Nanosponges that soak up a dangerous pore-forming toxin produced by MRSA (methicillin-resistant Staphylococcus aureus) could serve as a safe and effective vaccine against this toxin.
This "nanosponge vaccine" enabled the immune systems of mice to block the adverse effects of the alpha-haemolysin toxin from MRSA—both within the bloodstream and on the skin. Nanoengineers from the University of California, San Diego described the safety and efficacy of this nanosponge vaccine in the December 1 issue of ...
04.12.2013 | Health and Medicine
04.12.2013 | Materials Sciences
04.12.2013 | Ecology, The Environment and Conservation
04.12.2013 | Event News
12.11.2013 | Event News
29.10.2013 | Event News