Men with cardiovascular disease may be at considerably increased risk for death even when their blood sugar level remains in the "normal" range, suggests a new study by a team of scientists at UCLA and Cedars-Sinai Medical Center in Los Angeles. The study, a statistical analysis examining the connection between glucose (blood sugar) levels and death in patients with cardiovascular disease, will be published Feb. 15 in the American Journal of Epidemiology, the leading scientific journal in its field.
Cardiovascular disease includes coronary heart disease, stroke, angina and peripheral vascular disease. Currently, doctors consider a glucose level of 100 or less to be normal, 101–126 to be impaired and above 126 to be diabetic.
"Our findings suggest that for men with cardiovascular disease, there is apparently no normal blood sugar level," said Sidney Port, UCLA professor emeritus of mathematics and statistics, and lead author of the study. "For these men, across the normal range, the lower their blood sugar, the better. Their death rate over a two-year period soars from slightly more than 4 percent at a glucose level of 70 (mg/dl) to more than 12 percent at 100 (mg/dl) -- an enormous increase."
Stuart Wolpert | EurekAlert!
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