A review on the neuropsychological aspects of bipolar disorder (alternations of mania and depression) by the group of Eduard Vieta (university of Barcelona) points to impairments in intellectual functioning in this patient population. The review was published in the 2006 March issue of Psychotherapy & Psychosomatics.
More and more epidemiological, genetic and neuroimaging studies show similarities between bipolar disorder (BD) and schizophrenia (SZ). Cognitive functions are known to be highly impaired in SZ and are increasingly studied in BD. When both populations are compared, the conclusions appear to be contradictory. The purpose of this review is to help define the profile of cognitive deficits in BD and in SZ.
A systematic review of the literature of neuropsychological studies comparing BD and SZ was made, beginning in January 1990 and ending in January 2005. Thirty-eight studies met the required quality criteria and were included in this review. Bipolar patients exhibit extensive cognitive abnormalities with a pattern of deficits that is not unique to this disease.
Eduard Vieta, MD, PhD | alfa
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