Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Columbia study shows depression intensifies from one generation to the next

11.01.2005


20-year study at Columbia University Medical Center is first to highlight increased risk of depression across three generations



Nearly 60 percent of children whose parents and grandparents suffered from depression have a psychiatric disorder before they reach their early teens, according to a new study by researchers at Columbia University Medical Center (CUMC) and the New York State Psychiatric Institute (NYSPI). This is more than double the number of children (approx. 28 percent) who develop such disorders with no family history of depression.

The study, published in the January issue of the Archives of General Psychiatry, is the first to follow three generations of high-risk families and has taken more than two decades to complete. The CUMC/NYSPI research team began studying 47 first generation family members in 1982; then interviewed 86 of their children several times as they grew into adulthood. The team has collected data from 161 members of the third generation, whose average age is 12.


Results found that most of the prepubescent grandchildren with a two-generation history of depression developed anxiety disorders that developed into depression as they aged into adolescence. This trend was also found when the researchers previously followed the children’s parents through adolescence and adulthood.

"We have shown that the risk of depression is carried through several generations and that it intensifies as more generations are affected," said the study’s lead author, Myrna Weissman, Ph.D., Professor of psychiatry and epidemiology at Columbia University Medical Center and Chief of the Department of Clinical & Genetic Epidemiology at New York State Psychiatric Institute. "Children with a two-generation family history of depression develop anxiety disorders earlier than other children and tend to experience more impairment." Other investigators involved included Priya Wickramaratne, Ph.D. and Virginia Warner, MPH.

Previous studies have shown that the children of a depressed parent are at greater risk of mood and anxiety disorders, but the Columbia study is the first to illustrate how the risk intensifies across three generations.

"Children of parents and grandparents with depression are at extremely high risk for mood and anxiety disorders even when they’re very young," Dr. Weissman says. "They should be considered for treatment if they develop anxiety disorders, or at least monitored very closely."

Craig LeMoult | EurekAlert!
Further information:
http://www.columbia.edu

More articles from Social Sciences:

nachricht Fixating on faces
26.01.2017 | California Institute of Technology

nachricht Internet use in class tied to lower test scores
16.12.2016 | Michigan State University

All articles from Social Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>