On January 1, 2013, the German Research Foundation (DFG) will establish a new Collaborative Research Center (CRC) at the University Medical Center of Johannes Gutenberg University Mainz (JGU). The research team of scientists from Mainz and Frankfurt, coordinated by Professor Dr. Robert Nitsch, Director of the Institute of Microscopic Anatomy and Neurobiology at the Mainz University Medical Center, has been awarded funding of approximately EUR 9.3 million for an initial period of four years.
The purpose of the CRC is to study the molecular and cellular interactions that enable the brain to maintain a balanced functional state in the form of network homeostasis. By gaining a more in-depth understanding of these mechanisms, the scientists involved also hope to provide new insights into disease processes in the brain, so that it becomes possible in the long term to develop new treatment options.The main aim of CRC 1080 "Molecular and Cellular Mechanisms of Neuronal Homeostasis" is to understand the molecular and cellular mechanisms of network homeostasis in detail. If successful, it should provide the ideal requirements for the development of medications to treat cerebral diseases in humans. Specifically, Nitsch's team of researchers intends to study various classes of molecules, such as those relevant to the control of cell-to-cell interactions and signaling processes. According to Nitsch, insight in this area is the key to understanding the importance of homeostatic mechanisms in the body, in particular in relation to disorders of the human nervous system.
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