MIT engineers report a new approach to creating three-dimensional samples of human tissue that could push researchers closer to their ultimate goal: tissues for therapeutic applications and replacement organs. The technique could also help answer questions in cell and developmental biology.
The team "seeded" human embryonic stem cells, which have the potential to differentiate into a variety of specialized cells, onto a biodegradable polymer scaffold. By treating the scaffold/stem cell structure with chemical cues, or growth factors, known to stimulate the formation of specific cell types, the researchers coaxed the stem cells to form tissues with characteristics of developing human cartilage, liver, nerves and blood vessels.
"Here we show for the first time that polymer scaffolds … promoted proliferation, differentiation and organization of human embryonic stem cells into 3D structures," the researchers wrote in a paper to appear the week of Oct. 13 in the online edition of the Proceedings of the National Academy of Sciences.
Elizabeth A. Thomson | EurekAlert!
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On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.
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At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
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Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
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