Using laser light as tweezers and a scalpel, scientists from the National Institute of Standards and Technology (NIST) have demonstrated the use of artificial cells as nanovials for ultrasmall volume chemistry. The approach may be useful for faster, cheaper identification of new pharmaceuticals and for studying cellular-level processes. The researchers will report their results in the Sept. 30 edition of Langmuir.
A series of three photos show two lipsomes fusing into one.
The artificial cells, called liposomes, are tiny spherical containers that self-assemble from natural fats (phospholipids and cholesterol). Measuring micrometers in diameter, the fluid-filled membranes are currently used in cosmetics and for drug delivery.
The NIST team developed an improved method for using liposomes as tiny test tubes for mixing chemicals with volumes measured in trillionths of liters. Their experimental setup allows simultaneous trapping of two liposomes without deforming or stressing their membranes, a problem with some other techniques. They used pairs of infrared lasers ("optical tweezers") to bring two liposomes into contact and a single ultra-violet laser pulse (the "optical scalpel") to fuse the two cells together. Once fused, the contents of the two cells mix and react. One liposome in each pair contained fluorescent dye, and the other contained calcium ions. After the cells merged, fluorescence increased as a result of the reaction between the dye and the ions.
Laura Ost | NIST
Applying electron beams to 3-D objects
23.09.2016 | Fraunhofer-Institut für Organische Elektronik, Elektronenstrahl- und Plasmatechnik FEP
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The Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP has been developing various applications for OLED microdisplays based on organic semiconductors. By integrating the capabilities of an image sensor directly into the microdisplay, eye movements can be recorded by the smart glasses and utilized for guidance and control functions, as one example. The new design will be debuted at Augmented World Expo Europe (AWE) in Berlin at Booth B25, October 18th – 19th.
“Augmented-reality” and “wearables” have become terms we encounter almost daily. Both can make daily life a little simpler and provide valuable assistance for...
With the help of artificial intelligence, chemists from the University of Basel in Switzerland have computed the characteristics of about two million crystals made up of four chemical elements. The researchers were able to identify 90 previously unknown thermodynamically stable crystals that can be regarded as new materials. They report on their findings in the scientific journal Physical Review Letters.
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For the first time, Fraunhofer IKTS shows additively manufactured hardmetal tools at WorldPM 2016 in Hamburg. Mechanical, chemical as well as a high heat resistance and extreme hardness are required from tools that are used in mechanical and automotive engineering or in plastics and building materials industry. Researchers at the Fraunhofer Institute for Ceramic Technologies and Systems IKTS in Dresden managed the production of complex hardmetal tools via 3D printing in a quality that are in no way inferior to conventionally produced high-performance tools.
Fraunhofer IKTS counts decades of proven expertise in the development of hardmetals. To date, reliable cutting, drilling, pressing and stamping tools made of...
At AKL’16, the International Laser Technology Congress held in May this year, interest in the topic of process control was greater than expected. Appropriately, the event was also used to launch the Industry Working Group for Process Control in Laser Material Processing. The group provides a forum for representatives from industry and research to initiate pre-competitive projects and discuss issues such as standards, potential cost savings and feasibility.
In the age of industry 4.0, laser technology is firmly established within manufacturing. A wide variety of laser techniques – from USP ablation and additive...
Every three years, the plastics industry gathers at K, the international trade fair for plastics and rubber in Düsseldorf. The Fraunhofer Institute for Laser Technology ILT will also be attending again and presenting many innovative technologies, such as for joining plastics and metals using ultrashort pulse lasers. From October 19 to 26, you can find the Fraunhofer ILT at the joint Fraunhofer booth SC01 in Hall 7.
K is the world’s largest trade fair for the plastics and rubber industry. As in previous years, the organizers are expecting 3,000 exhibitors and more than...
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23.09.2016 | Life Sciences
23.09.2016 | Health and Medicine
23.09.2016 | Life Sciences