Using laser light as tweezers and a scalpel, scientists from the National Institute of Standards and Technology (NIST) have demonstrated the use of artificial cells as nanovials for ultrasmall volume chemistry. The approach may be useful for faster, cheaper identification of new pharmaceuticals and for studying cellular-level processes. The researchers will report their results in the Sept. 30 edition of Langmuir.
A series of three photos show two lipsomes fusing into one.
The artificial cells, called liposomes, are tiny spherical containers that self-assemble from natural fats (phospholipids and cholesterol). Measuring micrometers in diameter, the fluid-filled membranes are currently used in cosmetics and for drug delivery.
The NIST team developed an improved method for using liposomes as tiny test tubes for mixing chemicals with volumes measured in trillionths of liters. Their experimental setup allows simultaneous trapping of two liposomes without deforming or stressing their membranes, a problem with some other techniques. They used pairs of infrared lasers ("optical tweezers") to bring two liposomes into contact and a single ultra-violet laser pulse (the "optical scalpel") to fuse the two cells together. Once fused, the contents of the two cells mix and react. One liposome in each pair contained fluorescent dye, and the other contained calcium ions. After the cells merged, fluorescence increased as a result of the reaction between the dye and the ions.
Laura Ost | NIST
Innovative process for environmentally friendly manure treatment comes onto the market
03.05.2018 | Fraunhofer-Institut für Grenzflächen- und Bioverfahrenstechnik IGB
No compromises: Combining the benefits of 3D printing and casting
23.03.2018 | Fraunhofer-Institut für Produktionstechnik und Automatisierung IPA
The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.
Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...
A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...
At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
25.05.2018 | Event News
02.05.2018 | Event News
13.04.2018 | Event News
25.05.2018 | Event News
25.05.2018 | Machine Engineering
25.05.2018 | Life Sciences