Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Carefully Mixed Radiation Cocktail Reduces Collateral Damage In Breast Cancer Patients

01.08.2006
A carefully determined mixture of electron and x-ray beams precisely treated breast tumors while significantly reducing collateral skin damage in 78 patients, researchers will report on August 1 at the annual meeting of the American Association of Physicists in Medicine in Orlando. The key to choosing the right mixture of beams, as well as their individual properties, was a sophisticated computer approach developed by medical physicists Jinsheng Li, Ph.D. (Jinsheng.Li@fccc.edu) and Chang-Ming Ma, Ph.D. of Fox Chase Cancer Center in Philadelphia.

In treating shallow tumors such as those that occur in the breast, physicians have been turning to mixed-beam radiation therapy (MBRT), which employs separate beams of electrons and photons (x-rays). The two types of radiation complement one another, as electrons generally travel to shallow depths while the x-rays can penetrate to deeper parts of the tumor as needed.

However, each beam interacts in complex ways with its environment, making their exact path to the tumor region hard to predict. Nonetheless, physicists can calculate the probability for a given beam to follow a desired trajectory.

Therefore, Li and Ma use computers to simulate billions of trips of each beam to the unique landscape of each tumor. Gathering the statistics from these billions of trials, they determine the best beam properties and mixtures.

The computer simulations helped oncologists send accurately targeted doses for 78 breast cancer patients receiving "hypofractionated" treatments, in which the patients received fewer, but more potent, doses of radiation. The beams delivered all the radiation within a small margin of the tumor's edge, dramatically reducing radiation damage to surrounding healthy tissue. The researchers expect their approach to provide benefits for reducing collateral damage in the treatment of shallow tumors in the breast, chest wall, and head-and-neck region.

Associated Meeting Papers:
TU-D-224A-6, "Advanced Mixed Beam Therapy Using MERT and IMRT," Tuesday, August 1, 2006, 2:30 PM, Room 224 A. Click Here for Technical Abstract

WE-E-224C-3, "Advanced Mixed Beam Radiotherapy for Breast and Head and Neck," Wednesday, August 2, 4:24, Room 224A. Click Here for Technical Abstract

Presented at: 48th Annual Meeting of the American Association of Physicists in Medicine, July 30-August 3, 2006, Orange County Convention Center, Orlando, FL. Click Here for Meeting Homepage

ABOUT AAPM
AAPM is a scientific, educational, and professional organization of more than 6,000 medical physicists. Headquarters are located at the American Center for Physics in College Park, MD. Publications include a scientific journal ("Medical Physics"), technical reports, and symposium proceedings

Ben Stein | EurekAlert!
Further information:
http://www.aapm.org
http://www.aip.org

More articles from Physics and Astronomy:

nachricht Study offers new theoretical approach to describing non-equilibrium phase transitions
27.04.2017 | DOE/Argonne National Laboratory

nachricht SwRI-led team discovers lull in Mars' giant impact history
26.04.2017 | Southwest Research Institute

All articles from Physics and Astronomy >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Fighting drug resistant tuberculosis – InfectoGnostics meets MYCO-NET² partners in Peru

28.04.2017 | Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

 
Latest News

Wireless power can drive tiny electronic devices in the GI tract

28.04.2017 | Medical Engineering

Ice cave in Transylvania yields window into region's past

28.04.2017 | Earth Sciences

Nose2Brain – Better Therapy for Multiple Sclerosis

28.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>