New percolation model may allow researchers to study biochemistry at the atomic level
A new report in the May 24 Proceedings of the Royal Society of London. Series A: Mathematical and Physical Sciences announces a mathematical model that will help researchers understand "cell signaling" and learn how single atoms travel along the circuitous pathways in a cell.
The model is a new approach to look at percolation-the flow of a liquid or small particle through a porous material. In the simulation, materials pass through fields of complex, three- dimensional shapes, a scenario that is closer to realworld environments than existing two-dimensional models and models incorporating simpler shapes.
The model was developed by Ann Marie Sastry and Yun-Bo Yi, both of the University of Michigan. The researchers will use their findings in a larger study that will deploy sensor proteins inside a cell where the nanoscale devices will track the paths of ions.
The model reveals how the sensors might interact with the miniscule ions that contribute to such diseases as stroke, cardiovascular disease and cancer. With the proper experimental design, the researchers may be able to watch fundamental chemical reactions-at the molecular level-as they occur in living cells.
In addition to biological applications, the simulation will help researchers develop new materials by revealing better ways to craft porous substances. By understanding the properties of these types of materials, researchers can enhance conductivity in batteries, flow paths in filters and numerous other percolation mechanisms.
Sastry won a 1997 NSF Presidential Early Career Award for Scientists and Engineers (PECASE), the highest honor bestowed by the United States government on scientists and engineers beginning their independent research careers. The NSF support from that award contributed to the development of the percolation model.
Support for the work was also provided by the Defense Advanced Research Projects Agency (DARPA) and the Office of Naval Research through the Synthetic Multifunctional Materials Program, managed by Leo Christodoulou of DARPA, and the W.M. Keck Foundation.
NSF comments regarding the Sastry research group: "With her PECASE award, Ann Marie Sastry has expanded her research focus from a single area in mechanical engineering, materials processing, into a broad exploration to uncover fundamental knowledge. She has demonstrated an ability to take advantage of support to move beyond her own initial training and move out to address societal needs." - Delcie Durham, program director in NSFs Division of Design, Manufacture and Industrial Innovation who oversaw Sastrys five-year award
"Because of her interests and abilities, Sastry has attracted a diverse team of students and guided them to address core areas within mechanical engineering. Sastry has expanded her research to address fundamental issues in mathematics, biology and energy." - Delcie Durham
"Sastry has been an articulate voice for manufacturing as a viable research and educational endeavor and a proponent of diversity as a critical component of these efforts." -
Seeing the quantum future... literally
16.01.2017 | University of Sydney
Airborne thermometer to measure Arctic temperatures
11.01.2017 | Moscow Institute of Physics and Technology
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration
"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...
Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.
Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...
10.01.2017 | Event News
09.01.2017 | Event News
05.01.2017 | Event News
16.01.2017 | Power and Electrical Engineering
16.01.2017 | Information Technology
16.01.2017 | Power and Electrical Engineering