NIST physical scientist Joy Dunkers positions a polymer scaffold sample for imaging.
In the November issue of Optics Express*, National Institute of Standards and Technology (NIST) scientists describe a novel combination of microscopes that can peer deep into tissue-engineering scaffolds and monitor the growth and differentiation of cells ultimately intended to develop into implantable organs or other body-part replacements.
The new dual-imaging tool provides a much needed capability for the emerging tissue engineering field, which aims to regenerate form and function in damaged or diseased tissues and organs. Until now, scrutiny of this complicated, three-dimensional process has been limited to the top-most layers of the scaffolds used to coax and sustain cell development.
Composed of biodegradable polymers or other building materials, scaffolds are seeded with cells that grow, multiply, and assemble into three-dimensional tissues. Whether the cells respond and organize as intended in this synthetic environment depends greatly on the composition, properties, and architecture of the scaffolds’ porous interiors. Tools for simultaneously monitoring microstructure and cellular activity can help scientists to tease apart the essentials of this interactive relationship. In turn, such knowledge can speed development of tissue-engineered products ranging from skin replacements to substitute livers to inside-the-body treatments of osteoporosis.
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23.02.2017 | University of Wisconsin-Madison
Prediction: More gas-giants will be found orbiting Sun-like stars
22.02.2017 | Carnegie Institution for Science
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
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