Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New 3-D ultrasound could improve stroke diagnosis, care

28.04.2008
Using 3-D ultrasound technology they designed, Duke University bioengineers can compensate for the thickness and unevenness of the skull to see in real-time the arteries within the brain that most often clog up and cause strokes.

The researchers believe that these advances will ultimately improve the treatment of stroke patients, whether by giving emergency medical technicians (EMT) the ability to quickly scan the heads of potential stroke victims while in the ambulance or allowing physicians to easily monitor in real time the patients’ response to therapy at the bedside.

The results of the latest studies were reported online in the journal Ultrasound in Medicine & Biology. The research was supported by the National Institutes of Health and the Duke Translational Medicine Institute, with assistance from the Duke Echocardiography Laboratory.

“To our knowledge, this is the first time that real time 3-D ultrasound provided clear images of the major arteries within the brain,” said Nikolas Ivancevich, graduate student in Duke’s Pratt School of Engineering and first author of the paper. “Also for the first time, we have been able overcome the most challenging aspect of using ultrasound to scan the brain – the skull.”

The Duke laboratory, led by biomedical engineering professor Stephen Smith, has a long track record of modifying traditional 2-D ultrasound – like that used to image babies in utero – into more advanced 3-D scans, which can provide more detailed information. After inventing the technique in 1991, the team has shown its utility in developing specialized catheters and endoscopes for imaging the heart and blood vessels.

“This is an important step forward for scanning the vessels of the brain through the skull, and we believe that there are now no major technological barriers to ultimately using 3-D ultrasound to quickly diagnose stroke patients,” said Smith, senior author of the paper.

“I think it’s safe to say that within five to 10 years, the technology will be miniaturized to the point where EMTs in an ambulance can scan the brain of a stroke patient and transmit the results ahead to the hospital,” Smith continued. “Speed is important because the only approved medical treatment for stroke must be given within three hours of the first symptoms.”

Ultrasound devices emit sound waves and then create images by calculating the angle of the waves as they bounce back.

For their experiments, the Duke team studied 17 healthy people. After injecting them with a contrast dye to enhance the images, the researchers aimed ultrasound “wands,” or transducers, into the brain from three vantage points – the temples on each side of the head and upwards from the base of the neck. The temple locations were chosen because the skull is thinnest at these points.

Ivancevich took this approach one step further to compensate for the thickness and unevenness of the skull in one subject.

“The speed of the sound waves is faster in bone than it is in soft tissue, so we took measurements to better understand how the bone alters the movement of sound waves,” Ivancevich explained. “With this knowledge, we were able to program the computer to ‘correct’ for the skull’s interference, resulting in even clearer images of the arteries.”

The key to obtaining these images lies in the design of the transducer. In traditional 2-D ultrasound, the sound is emitted by a row of sensors. In the new design, the sensors are arranged in a checkerboard fashion, allowing compensation for the skull's thickness over a whole area, instead of a single line.

The 3-D ultrasound has the benefit of being less expensive and faster than the traditional methods of assessing blood flow in the brain – MRI or CT scanning, Ivancevich said. Though 3-D ultrasound will not totally displace MRI or CT scans, he said that the new technology would give physicians more flexibility in treating their patients.

Richard Merritt | EurekAlert!
Further information:
http://www.duke.edu

More articles from Physics and Astronomy:

nachricht APEX takes a glimpse into the heart of darkness
25.05.2018 | Max-Planck-Institut für Radioastronomie

nachricht First chip-scale broadband optical system that can sense molecules in the mid-IR
24.05.2018 | Columbia University School of Engineering and Applied Science

All articles from Physics and Astronomy >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

If solubilty is the problem - Mechanochemistry is the solution

25.05.2018 | Life Sciences

Investigating cell membranes: researchers develop a substance mimicking a vital membrane component

25.05.2018 | Interdisciplinary Research

When corals eat plastics

24.05.2018 | Ecology, The Environment and Conservation

VideoLinks
Science & Research
Overview of more VideoLinks >>>