Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Engineers demonstrate a new type of optical tweezer

26.02.2008
Microfabricated optical tweezer has the potential to make biological and microfluidic force measurements in integrated systems such as microfluidic chips

Researchers at the Harvard School of Engineering and Applied Sciences (SEAS) demonstrated a new type of optical tweezer with the potential to make biological and microfluidic force measurements in integrated systems such as microfluidic chips. The tweezer, consisting of a Fresnel Zone Plate microfabricated on a glass slide, has the ability to trap particles without the need for high performance objective lenses.

The device was designed, fabricated, and tested by postdoctoral fellow Ethan Schonbrun and undergraduate researcher Charles Rinzler under the direction of Assistant Professor of Electrical Engineering Ken Crozier (all are affiliated with SEAS). The team's results were published in the February 18th edition of Applied Physics Letters and the researchers have filed a U.S. provisional patent covering this new device.

"The microfabricated nature of the new optical tweezer offers an important advantage over conventional optical tweezers based on microscope objective lenses," says Crozier. "High performance objective lenses usually have very short working distances -- the trap is often ~200 mm or less from the front surface of the lens. This prevents their use in many microfluidic chips since these frequently have glass walls that are thicker than this."

The researchers note that the Fresnel Zone Plate optical tweezers could be fabricated on the inner walls of microfluidic channels or even inside cylindrical or spherical chambers and could perform calibrated force measurements in a footprint of only 100x100μm.

Traditional tweezers, by contrast, would suffer from crippling aberrations in such locations. Moreover, in experimental trials, the optical tweezers exhibited trapping performance comparable to conventional optical tweezers when the diffraction efficiency was taken into account.

The researchers envision using their new tweezer inside microfluidic chips to carry out fluid velocity, refractive index, and local viscosity measurements. Additional applications include biological force measurements and sorting particles based on their size and refractive index. Particle-sorting chips based on large arrays of tweezers could be used to extract the components of interest of a biological sample in a high-throughput manner.

Michael Patrick Rutter | EurekAlert!
Further information:
http://www.seas.harvard.edu

More articles from Physics and Astronomy:

nachricht From rocks in Colorado, evidence of a 'chaotic solar system'
23.02.2017 | University of Wisconsin-Madison

nachricht Prediction: More gas-giants will be found orbiting Sun-like stars
22.02.2017 | Carnegie Institution for Science

All articles from Physics and Astronomy >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Stingless bees have their nests protected by soldiers

24.02.2017 | Life Sciences

New risk factors for anxiety disorders

24.02.2017 | Life Sciences

MWC 2017: 5G Capital Berlin

24.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>