Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Flexible Electronics Could Help Put Off-Beat Hearts Back On Rhythm

Arrhythmic hearts soon may beat in time again, with minimal surgical invasion, thanks to flexible electronics technology developed by a team of University of Illinois researchers, in collaboration with the University of Pennsylvania School of Medicine and Northwestern University. These biocompatible silicon devices could mark the beginning of a new wave of surgical electronics.

Co-senior author John Rogers, the Lee J. Flory-Founder Chair in Engineering Innovation and a professor of materials science and engineering at Illinois, and his team will publish their breakthrough in the cover story of the March 24 issue of Science Translational Medicine.

Several treatments are available for hearts that dance to their own tempo, ranging from pacemaker implants to cardiac ablation therapy, a process that selectively targets and destroys clusters of arrhythmic cells. Current techniques require multiple electrodes placed on the tissue in a time-consuming, point-by-point process to construct a patchwork cardiac map. In addition, the difficulty of connecting rigid, flat sensors to soft, curved tissue impedes the electrodes’ ability to monitor and stimulate the heart.

Rogers and his team have built a flexible sensor array that can wrap around the heart to map large areas of tissue at once. The array contains 2,016 silicon nanomembrane transistors, each monitoring electricity coursing through a beating heart.

The Pennsylvania team demonstrated the transistor array on the beating hearts of live pigs, a common model for human hearts. They witnessed a high-resolution, real-time display of the pigs’ pulsing cardiac tissues – something never before possible.

“We believe that this technology may herald a new generation of devices for localizing and treating abnormal heart rhythms,” said co-sernior author Brian Litt, of the University of Pennsylvania.

“This allows us to apply the full power of silicon electronics directly to the tissue,” said Rogers, a renowned researcher in the area of flexible, stretchable electronics. As the first class of flexible electronics that can directly integrate with bodily tissues, “these approaches might have the potential to redefine design strategies for advanced surgical devices, implants, prosthetics and more,” he said.

The biocompatible circuits – the first ones unperturbed by immersion in the body’s salty fluids – represent a culmination of seven years of flexible electronics study by Rogers’ group. The researchers build circuits from ultrathin, single-crystal silicon on a flexible or stretchy substrate, like a sheet of plastic or rubber. The nanometer thinness of the silicon layer makes it possible to bend and fold the normally rigid semiconductor.

“If you can create a circuit that’s compliant and bendable, you can integrate it very effectively with soft surfaces in the body,” such as the irregular, constantly moving curves of the heart, Rogers said.

Collaborations with a theoretical mechanics group at Northwestern University, led by Younggang Huang, yielded important insights into the designs.

The patchwork grid of cardiac sensors adheres to the moist surfaces of the heart on its own, with no need for probes or adhesives, and lifts off easily. The array of hundreds of sensors gives cardiac surgeons a more complete picture of the heart’s electrical activity so they can quickly find and fix any short circuits. In fact, the cardiac device boasts the highest transistor resolution of any class of flexible electronics for non-display applications.

The team’s next step is to adapt the technology for use with non-invasive catheter procedures, Rogers said. The U. of I. and Pennsylvania teams also are exploring applications for the arrays in neuroscience, applying grids to brain surfaces to study conditions of unusual electrical activity, such as epilepsy.

“It sets out a new design paradigm for interfacing electronics to the human body, with a multitude of possible applications in human health,” Rogers said.

This work was supported by the U.S. Department of Energy, a National Security Science and Engineering Faculty Fellowship, the National Institutes of Health and the Klingenstein Foundation.

Editor’s note: To contact John Rogers, call 217-244-4979; e-mail

Liz Ahlberg | University of Illinois
Further information:

More articles from Physics and Astronomy:

nachricht Light-driven atomic rotations excite magnetic waves
24.10.2016 | Max-Planck-Institut für Struktur und Dynamik der Materie

nachricht Move over, lasers: Scientists can now create holograms from neutrons, too
21.10.2016 | National Institute of Standards and Technology (NIST)

All articles from Physics and Astronomy >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Oasis of life in the ice-covered central Arctic

24.10.2016 | Earth Sciences

‘Farming’ bacteria to boost growth in the oceans

24.10.2016 | Life Sciences

Light-driven atomic rotations excite magnetic waves

24.10.2016 | Physics and Astronomy

More VideoLinks >>>