The findings are in new research published in Diabetologia, the Journal of the European Association for the Study of Diabetes (EASD), and written by Dr Marcus Lind, Sahlgrenska Academy, University of Gothenburg, Sweden and colleagues.
A previous review of studied investigated diabetes mortality suggested that having diabetes increased a person’s mortality risk by 80% compared with the general population. However, many studies in the review were from before 2000, and some recent studies have suggested diabetes might increase mortality by less than this.
Thus in this new study, the authors estimated the current mortality rate ratio in patients with versus without diabetes and whether it has changed over time.
The UK and Canada were selected for analysis because the authors in both nations and Sweden are part of an ongoing collaboration, and this is a study objective that cannot be examined in many countries, since there are limited numbers of databases with long follow-up which are also population-based with mortality data on individuals both with and without diabetes. Both Canada and the UK hold such data.
The population-based databases from the province of Ontario, Canada, and The Health Improvement Network (THIN) database from the UK, from years 1996 to 2009 were used to calculate mortality rates in persons with and without diabetes.
The excess risk of mortality estimated during 2009 was 51% in Ontario and 65% in THIN for diabetic patients on a group level, compared to 90% and 114%, respectively, in the year 1996. The excess risk of mortality for diabetic patients declined to a similar extent for men and women over the study period, and no significant differences between sexes were observed in 2009.
“It is noteworthy that the prevalence of diabetes in Ontario (adults 20 years or older) increased from 5.4% to 11.4% over the study period, and in the THIN cohort there was an increase in prevalence from 3.2% to 5.9% over the corresponding time period,” says Lipscombe.
The excess risk of mortality for diabetic patients decreased in all age groups over time—approximately 25%-40% lower in age groups below 64 years and 50%-65% lower in those aged 64 years and older during the study period. In 2009 the excess risk of mortality for individuals with diabetes 20-44 years of age was 70%-80% in both cohorts. In those 45-64 years old, mortality was approximately doubled and was 15-25% greater in individuals 65 years of age and over.
The authors say that more aggressive treatment during recent decades may explain these results, including more intensive control of blood sugar in people with diabetes, and blood pressure control and statins to reduce the risk of cardiovascular events in people both with and without diabetes.
A shift towards more diabetes screening and earlier diagnosis in recent years may also have contributed to lower mortality rates within more contemporary diabetes populations.
Although not a primary focus of this study, the authors say it should be noted that the prevalence of diabetes was considerably higher in the Ontario cohort than in THIN during the study period. The reasons for this discrepancy are unclear, but may be related to differences in factors known to influence the incidence of diabetes such as screening programmes, ethnicity, eating habits or physical activity patterns between the two cohorts. Further research would be needed to explore these possibilities.
The authors conclude: “The excess risk of age-standardized mortality in patients with versus without diabetes has decreased over time in both Canada and the UK, having fallen to an increased risk of 50-65% in 2009. The excess risk related to diabetes however varies by age:70%-80% in individuals 20-44 years of age, approximately double in those aged 45-64 years, and 15%-25% greater in individuals above age 65 years and over.”
For more information please contact:
Dr Marcus Lind, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. T) +46 (0)738 31 17 42 / +46-(0)10-4350000 E) firstname.lastname@example.org / email@example.com
Dr Lorraine Lipscombe, Women’s College Hospital, Women’s College Research Institute, Toronto, ON, Canada, please contact Julie Saccone in Communications Department. T) +1 416-323-6400, ext.4054
E) firstname.lastname@example.org / Lorraine.Lipscombe@wchospital.ca
Alternative contact: Tony Kirby at Tony Kirby PR Ltd T) +44 7834 385827 E)
Further Reports about: blood sugar > cardiovascular events > diabetes mortality > diabetic patients > Gothenburg > mortality rate > oak mortality rates > Ontario > risk of mortality > screening programme > Thin
More articles from Health and Medicine:
Recurring memory traces boost long-lasting memories
05.12.2013 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)
Gentler Heart Surgery remains without signs of Dementia
05.12.2013 | Rheinische Friedrich-Wilhelms-Universität Bonn
The Light: Global study gets underway with online user survey
Light has a fundamental impact on our sense of well-being and performance. In cooperation with Zumtobel, a supplier of lighting solutions, Fraunhofer IAO has launched a global user survey of lighting quality in offices. The objective is to identify the best lighting conditions for a variety of spaces and lighting ...
Quantum entanglement, a perplexing phenomenon of quantum mechanics that Albert Einstein once referred to as “spooky action at a distance,” could be even spookier than Einstein perceived.
Physicists at the University of Washington and Stony Brook University in New York believe the phenomenon might be intrinsically linked with wormholes, hypothetical features of space-time that in popular science fiction can provide a much-faster-than-light shortcut from one part of the universe to another.
But here’s the catch: One couldn’t actually ...
A star is formed when a large cloud of gas and dust condenses and eventually becomes so dense that it collapses into a ball of gas, where the pressure heats the matter, creating a glowing gas ball – a star is born.
New research from the Niels Bohr Institute, among others, shows that a young, newly formed star in the Milky Way had such an explosive growth, that it was initially about 100 times brighter than it is now. The results are published in the scientific journal, Astrophysical Journal Letters.
The young ...
EPFL scientists have shown how to achieve a dramatic increase in the capacity of optical fibers; Their simple, innovative solution reduces the amount of space required between the pulses of light that transport data
Optical fibers carry data in the form of pulses of light over distances of thousands of miles at amazing speeds. They are one of the glories of modern telecommunications technology.
However, their capacity is limited, because the pulses of light need to be lined up one after the other in ...
NASA's Hurricane and Severe Storms Sentinel airborne mission known as HS3 wrapped up for the 2013 Atlantic Ocean hurricane season at the end of September, and had several highlights. HS3 will return to NASA’s Wallops Flight Facility in Wallops Island, Va., for the 2014 Atlantic hurricane season.
During the 2013 mission, two unmanned Global Hawks flew from Wallops for the first time. The mission highlights included studying the Saharan Air Layer, following the genesis of a tropical storm, finding a unique hybrid core or center circulation in a redeveloped storm, obtaining measurements on the strongest side of ...
05.12.2013 | Health and Medicine
05.12.2013 | Ecology, The Environment and Conservation
05.12.2013 | Information Technology
05.12.2013 | Event News
04.12.2013 | Event News
12.11.2013 | Event News