The researchers hope the advanced technology will be helpful in predicting the onset of Alzheimer's disease. The test, which is featured in the current online issue of The American Journal of Alzheimer's Disease and Other Dementias, is helping researchers further understand the role of the brain structures critical to human memory.
Individuals who have been diagnosed with MCI show memory loss but relatively preserved abilities in other cognitive areas. However, many individuals with MCI appear to be at a higher risk for developing other forms of dementia, including Alzheimer's disease. Accordingly, individuals with MCI play an important role in the development of research strategies that could lead to early diagnosis and possible prevention of such dementias.
To study the brain changes related to memory loss, Yerkes director and lead researcher Stuart Zola, PhD, developed an infrared eye-tracking test that involves showing individuals one image and then another after a several-second delay. The researchers then repeat the test several minutes later. In doing so, they found patients with MCI spent less time looking at the new picture than control subjects.
"Someone without any impairment spends most of the time focusing on the new image because the person quickly recognizes the previously shown image," says Zola. In contrast, individuals with MCI show less interest in the new image because, as time passes, they may not remember seeing the original image. This is similar to individuals with Alzheimer's disease, who will look at both images equally because they cannot remember seeing the first image," Zola continues.
The results of the study indicate the possibility of detecting dementias much earlier than ever before. By doing so, intervention can begin sooner, which offers hope for more effective treatment and, thus, encouraging outcomes. The researchers plan to follow up the study by tracking and observing study participants to determine whether they develop any forms of dementia.
To listen to Zola's own words about his research involving diagnosing cognitive impairment, access Emory's new Sound Science podcast at http://whsc.emory.edu/soundscience/.
For nearly eight decades, the Yerkes National Primate Research Center, Emory University, has been dedicated to conducting essential basic science and translational research to advance scientific understanding and to improve the health and well-being of humans and nonhuman primates. Today, the center, as one of only eight National Institutes of Health–funded national primate research centers, provides leadership, training and resources to foster scientific creativity, collaboration and discoveries. Yerkes-based research is grounded in scientific integrity, expert knowledge, respect for colleagues, an open exchange of ideas and compassionate, quality animal care.
Within the fields of microbiology and immunology, neuroscience, psychobiology and sensory-motor systems, the center's research programs are seeking ways to: develop vaccines for infectious and noninfectious diseases, such as AIDS and Alzheimer's disease; treat cocaine addiction; interpret brain activity through imaging; increase understanding of progressive illnesses such as Parkinson's and Alzheimer's; unlock the secrets of memory; determine behavioral effects of hormone replacement therapy; address vision disorders; and advance knowledge about the evolutionary links between biology and behavior.
The Robert W. Woodruff Health Sciences Center of Emory University is an academic health science and service center focused on missions of teaching, research, health care and public service. Its components include the Emory University School of Medicine, Nell Hodgson Woodruff School of Nursing, and Rollins School of Public Health; Yerkes National Primate Research Center; Emory Winship Cancer Institute; and Emory Healthcare, the largest, most comprehensive health system in Georgia. Emory Healthcare includes: The Emory Clinic, Emory-Children's Center, Emory University Hospital, Emory University Hospital Midtown, Wesley Woods Center, Emory University Orthopaedics & Spine Hospital, the jointly owned Emory-Adventist Hospital, and EHCA, a limited liability company created with Hospital Corporation of America. EHCA includes two joint venture hospitals, Emory Eastside Medical Center and Emory Johns Creek Hospital. The Woodruff Health Sciences Center has a $2.3 billion budget, 18,000 employees, 2,500 full-time and 1,500 affiliated faculty, 4,300 students and trainees, and a $5.5 billion economic impact on metro Atlanta.
Lisa Newbern | EurekAlert!
Further reports about: > Alzheimer's Disease > EHCA > Eye Tracking > Healthcare > Immunology > MCI > Mild Dementia > Neuroscience > Science TV > brain structure > dementia > hormone replacement therapy > human memory > infrared eye-tracking > memory loss > mild cognitive impairment > nonhuman primates > primate > sensory-motor systems
New study points the way to therapy for rare cancer that targets the young
22.11.2017 | Rockefeller University
Penn study identifies new malaria parasites in wild bonobos
21.11.2017 | University of Pennsylvania School of Medicine
Heat from the friction of rocks caused by tidal forces could be the “engine” for the hydrothermal activity on Saturn's moon Enceladus. This presupposes that...
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
15.11.2017 | Event News
15.11.2017 | Event News
30.10.2017 | Event News
23.11.2017 | Information Technology
23.11.2017 | Physics and Astronomy
23.11.2017 | Life Sciences