Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Wheezing After Early-Life Antibiotics: Blame the Underlying Chest Infection More Than the Antibiotics

07.08.2008
Children who are given antibiotics in their first three months often wheeze at 15 months of age. However, this wheezing is probably more due to the presence of chest infections than to the use of antibiotics.

These were the key findings of research carried out by researchers in New Zealand, and published in this month’s edition of Clinical and Experimental Allergy.

This work built on the fact that the prevalence both of asthma and the use of antibiotics have risen since the 1960s. Using antibiotics reduces a person’s exposure to bacterial infections and disturbs healthy populations of bacteria in the body, and the question is whether this then leaves a person more prone to develop asthma.

The researchers recruited a group of 1,000 babies at birth and contacted the parents at 3 months, 15 months and then yearly until they were four years old. Each time, they collected data about chest infections, asthma and their use of antibiotics. The data showed that by the time the children had reached 15 months old, nearly three quarters (72.1%) had been given antibiotics. In addition 11.8% had asthma, 39.6% had eczema and 21.2% had a recurring itchy scaly rash.

The researchers then looked at the data to see whether there was any indication that the antibiotics caused these effects and found that by adjusting for the effects of chest infections the association between antibiotics and wheezing was very much reduced.

"Our results strongly suggest that the reason that some children who have been given antibiotics appear to develop asthma is because they had a chest infection and the symptoms of the chest infection in young children can be confused with the start of asthma,” says Julian Crane, a senior study investigator at the Wellington Asthma Research Group in Wellington, New Zealand. “Antibiotics are given to treat the respiratory condition and rather than being a cause of asthma, as has been previously suggested, they are used for chest infections which can indicate an increased risk of asthma, or be mistaken for it.”

One of the underlying issues is that it is often difficult to distinguish between asthma and chest infections at an early age. Consequently some infants who are given antibiotics to cure a chest infection may really have been suffering from the early symptoms of asthma.

“Our data still leaves open the possibility that antibiotics may affect the development of eczema and itchy skin by four years and allergic hypersensitivity by 15 months,” says Crane.

Jennifer Beal | alfa
Further information:
http://www.wiley.co.uk

More articles from Health and Medicine:

nachricht How cancer metastasis happens: Researchers reveal a key mechanism
19.01.2018 | Weill Cornell Medicine

nachricht Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Let the good tubes roll

19.01.2018 | Materials Sciences

How cancer metastasis happens: Researchers reveal a key mechanism

19.01.2018 | Health and Medicine

Meteoritic stardust unlocks timing of supernova dust formation

19.01.2018 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>