For the study, researchers followed for eight years 1,836 Japanese Americans in Washington state with an average age of 72. During that time, 129 people developed dementia.
The research found that people with lower body mass index (BMI) scores at the beginning of the study were 79 percent more likely to develop dementia than those with higher BMI scores.
In addition, those who lost weight over the study period at a faster rate were nearly three times more likely to develop dementia than those who lost weight more slowly over time. This result was more pronounced in those who were overweight or obese to start; those with a BMI of 23 or higher had an 82-percent reduced risk of developing the disease compared to those who were normal or underweight. The results were the same after testing for other health risk factors such as smoking, exercise and gender.
“Our finding suggests that losing weight quickly in older age may be an early sign of dementia,” said study author Tiffany Hughes, PhD, MPH, who is with the University of Pittsburgh School of Medicine but conducted the research while she was a doctoral student at the University of South Florida. “This doesn’t mean that being obese or overweight is healthy for the mind or body, but losing weight may be a sign of emerging brain disease.”
Hughes says other current research shows that, in contrast, a larger belly in midlife may be a risk factor for dementia.
“Dementia has been shown to develop in the brain decades before any symptoms develop,” Hughes said. “These findings likely reflect that process. In middle age, obesity may be a risk factor for dementia, while declining weight in late life may be considered one of the first changes from the disease that occurs before it actually affects a person’s memory.”
The American Academy of Neurology, an association of more than 21,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as multiple sclerosis, restless legs syndrome, Alzheimer’s disease, narcolepsy, and stroke.
Penn vet research identifies new target for taming Ebola
12.01.2017 | University of Pennsylvania
The strange double life of Dab2
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Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration
"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...
Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.
Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...
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16.01.2017 | Power and Electrical Engineering