"Our research team has long hoped to be able to target radiotherapy in this way," says oncologist Håkan Andersson from Sahlgrenska University Hospital, who is leading the research alongside professor Ragnar Hultborn from the Sahlgrenska Academy and radiation physicist Lars Jacobsson.
"There is a good chance of this treatment working, as the study indicates that a sufficient amount of the active substance reaches the tumour cells in the abdominal cavity without any measurable side-effects."
The aim of this initial patient study, just published in the Journal of Nuclear Medicine, was to study the substance's distribution in the body and any side-effects in nine women with ovarian cancer.
"We have previously seen that mice with ovarian cancer given this treatment are generally cured without serious side-effects, so we hope that this will become an established and effective treatment for women with metastatic ovarian cancer," says Ragnar Hultborn, professor of oncology at the University of Gothenburg's Sahlgrenska Academy. "But it will still be several years of development."
The research is being funded partly by the Swedish Research Council and the Swedish Cancer Society.
"In our next study, 80 women with ovarian cancer will receive this treatment as a supplement to their ordinary treatment so that we can scientifically test whether the effect is as good in real patients as the animal studies indicate," Håkan Andersson says.OVARIAN CANCER
Partners in clinical research The Sahlgrenska Academy is the University of Gothenburg's health sciences faculty, while Sahlgrenska University Hospital is one of northern Europe's largest hospitals. The two institutions have almost 300 different joint research projects under way. Their strongest research fields include obesity with cardiovascular research and diabetes, biomaterials, pharmacology, neuroscience, paediatrics, epidemiology, rheumatology and microbiology.
Helena Aaberg | idw
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Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.
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For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.
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