Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Traumatic childhood may increase the risk of drug addiction

31.08.2012
Research examines the link between a traumatic upbringing and personality traits which increase the risk of addiction

Previous research has shown that personality traits such as impulsivity or compulsiveness are indicators of an increased risk of addiction. Now, new research from the University of Cambridge suggests that these impulsive and compulsive personality traits are also associated with a traumatic upbringing during childhood. The study was published today, 31 August, in the journal American Journal Psychiatry.

Led by Dr Karen Ersche, the Cambridge researchers aimed to identify risk factors that make a person vulnerable to developing drug dependence. They examined 50 adults with cocaine dependence together with their biological brothers and sisters who have never abused drugs. All participants underwent extensive assessments of their personalities, including their ways of feeling and thinking. The researchers were also interested in negative experiences that participants may have had during childhood (to include physical, emotional or sexual abuse).

Dr Ersche, of the Behavioural and Clinical Neuroscience Institute (BCNI) at the University of Cambridge, said: "It has long been known that abusive experiences during childhood have long-lasting effects on behaviour in adulthood and this was confirmed by our results. The siblings had more troubled childhoods compared to healthy peers in the community, and we also found a direct relationship between traumatic childhoods and their personalities."

She added: "This relationship is interesting because impulsive personality traits are known to increase the risk of becoming addicted to drugs but it is not an excuse for drug-taking."

The childhoods of the brothers and sisters of the cocaine-dependent individuals were also traumatic, and they also exhibited higher-than-normal levels of impulsive and compulsive behaviours, but they did not abuse drugs.

The researchers next intend to explore how the siblings who do not abuse drugs managed to deal with their traumatic childhoods and their highly impulsive and compulsive personalities. The scientists want to understand what makes the siblings resilient against addiction. A better understanding of what protected the brothers and sisters from drug abuse may provide vital clues for developing more effective therapeutic interventions for those trying to beat their addiction.

Dr Ersche added: "Not all individuals with these personality traits would have had a traumatic upbringing. Nor does everyone with these traits develop an addiction. However, our findings show that some people are particularly at risk and their upbringing may have contributed to it."

The study was funded by the Medical Research Council and conducted within the Behavioural and Clinical Neuroscience Institute at the University of Cambridge, which is co-funded by the MRC and the Wellcome Trust.

For additional information please contact:

Genevieve Maul, Office of Communications, University of Cambridge
Tel: direct, +44 (0) 1223 765542, +44 (0) 1223 332300
Mob: +44 (0) 7774 017464
Email: Genevieve.maul@admin.cam.ac.uk
Notes to editors:
1. The paper 'Cognitive Dysfunction and Anxious-Impulsive Personality Traits Are Endophenotypes for Drug Dependence' will be published online 31 August on American Journal Psychiatry website.

2. For almost 100 years the Medical Research Council has improved the health of people in the UK and around the world by supporting the highest quality science. The MRC invests in world-class scientists. It has produced 29 Nobel Prize winners and sustains a flourishing environment for internationally recognised research. The MRC focuses on making an impact and provides the financial muscle and scientific expertise behind medical breakthroughs, including one of the first antibiotics penicillin, the structure of DNA and the lethal link between smoking and cancer. Today MRC funded scientists tackle research into the major health challenges of the 21st century.

Genevieve Maul | EurekAlert!
Further information:
http://www.cam.ac.uk

More articles from Health and Medicine:

nachricht A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital

nachricht Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

DGIST develops 20 times faster biosensor

24.04.2017 | Physics and Astronomy

Nanoimprinted hyperlens array: Paving the way for practical super-resolution imaging

24.04.2017 | Materials Sciences

Atomic-level motion may drive bacteria's ability to evade immune system defenses

24.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>