Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

On the track of diseases of civilization - LIFE starts

08.09.2010
In Leipzig a worldwide unique LIFE research program starts with 30,000 participants Biggest German project targeting widespread diseases of our time is ready for take-off: worldwide for the first time, the Leipzig Research Centre for Civilization Diseases, LIFE, will study the interaction between genetic composition, metabolism and individual lifestyle on a big scale at a single location.

With almost 40 Mio €, population and patient surveys are supposed to yield ground-breaking findings on the causes of the most important diseases of civilization and to advance the biomedical economic region of Leipzig. As a result, new diagnostic and therapeutic approaches are expected. To this end, starting this fall a consortium of more than 100 physicians and scientists will examine more than 30,000 Leipzig residents. In the focus: disorders of blood vessels and heart attack, Diabetes mellitus, adiposity, depression, dementia, pancreatic inflammations, head and neck tumors as well as allergies and metabolic dysfunctions.

LIFE Background:

“It still remains a secret why some people stay healthy for a long time and grow very old despite known risk factors such as high cholesterol and excessive weight. On the other hand, more and more young people suffer already from lifestyle-borne diseases without us being able to predict the causes”, explains Professor Joachim Thiery, member of the LIFE board of directors and head of the Institute of Laboratory Medicine at the university Medical Center Leipzig. “This is why we intend to bring together at a single location thousands of scientific research results, which recognize the human being in its entirety – genes and function of organs, lifestyle and environmental conditions”, Thiery explains, who is also the dean of the university’s Medical Faculty. The LIFE project will provide ground-breaking insights into the molecular characteristics of man and its interplay with our modern world. It is the biggest scientific undertaking of the Free State of Saxony’s excellence initiative. In LIFE, cutting-edge technologies in imaging, genome and laboratory analytics will be used. At the same time, detailed information regarding lifestyle and individual conditions of living will be collected from all participants of the study.

Worldwide unique is a partially mechanized biobank, in which more than 1 Mio blood and cell samples will be stored in liquid nitrogen for future analysis. “An invaluable treasure for future cutting-edge research in Leipzig, for generations of scientist to come and for therapies of tomorrow”, said Professor Daniel Teupser, who heads the biobank as a laboratory physician and LIFE professor of genetics.

All samples and surveys will be pseudonymously entered into a huge data base and analyzed mathematically. “To this end, 17,000 patients of the university’s Medical Center – their agreement after proper information provided – will ‘donate’ the findings of their examination, which then will be compared to the results obtained by analyzing 15,000 volunteers from the Leipzig population – among them 5,000 children and adolescents, which will be supervised by the director of the university’s Pediatric Clinic”, Professor Markus Löffler stressed, who is the responsible medical statistician, member of the LIFE board of directors and head of the Institute of Medical Informatics, Statistics and Epidemiology. “Assisted by the Leipzig registration office we will ask tens of thousands of Leipzig residents by mail to participate in this big LIFE project. Each participant will be able to take the collected individual health data home to his or her general practitioner.”

In cooperation with research institutes from the Max-Planck and the Helmholtz Societies as well as from industry, the physicians and scientists of the LIFE center intend to provide first medically and economically exploitable results already within the next two to three years. “I am convinced, we will gain seminal and completely novel insights into one or two of the great diseases of civilization, thus paving the way for improved prophylaxis and much more targeted therapy as is possible today”, says Professor Thiery. The reviewers from the German Research Community are equally convinced as are the funding agencies, the European Union (32 Mio € from EFRE funds, 1.3 Mio € from ESF funds for junior researchers) and the Free State of Saxony (6 Mio €).

Press Conference Research Centre for Civilization Diseases (LIFE)

Time: 27.09.2010, 10:30 h
Location: Carl-Ludwig Institute for Physiology (CLI), Conference Room at Dean’s Office, Medical Faculty/Clinical Center, University of Leipzig
Room: Lecture Hall/Second Floor
Liebigstr. 27
04103 Leipzig
Discussion partners:
Prof. Dr. med. Joachim Thiery,
Member of LIFE board of directors and dean of the Medical Faculty of the University of Leipzig
Prof. Dr. med. Markus Löffler,
Member of LIFE board of directors and head of the Institute of Medical Informatics, Statistics and Epidemiology, University of Leipzig
Prof. Daniel Teupser,
Professor for Clinical Chemistry and Functional Genetics, head of LIFE biobank
Prof. Wieland Kiess,
Head of hospital and policlinic for children and adolescence
Registration and arrangement of interviews and dates for camera and photo shootings:
Sebastian Späthe
Scientific public relations consultant
sebastian.spaethe@life.uni-leipzig.de
Phone: +49 341 9716723
Mobile: +49 163 3025756
Fax: +49 341 9716729

Dr. Manuela Rutsatz | idw
Further information:
http://www.uni-leipzig.de
http://www.uni-leipzig-life.de/

More articles from Health and Medicine:

nachricht Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences

nachricht What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>