Hospitals across the country have seen sharp declines in rates of central line-associated blood stream infections (CLABSIs) and ventilator-associated pneumonias (VAPs) among critically ill neonates and children, according to a new study in the journal Pediatrics.
The study, "Health care-associated infections among critically ill children in the U.S.," analyzed incidences rates of CLABSIs, VAPs and catheter-associated urinary tract infections (CAUTIs) for 173 neonatal intensive care units (NICUs) and 64 pediatric intensive care units (PICUs) from 2007-2012.
"Central lines, ventilators and urinary catheters are commonly required as part of lifesaving medical care for critically ill neonates and children," said lead author Stephen Patrick M.D., MPH, MS, assistant professor of Pediatrics and Health Policy in the Division of Neonatology at Monroe Carell Jr. Children's Hospital at Vanderbilt.
"When you use devices such as these in clinical care it makes children more vulnerable to infections. Over the last several years in neonatal and pediatric intensive care units around the country, we began to pay attention to the high rates of hospital-associated infections.
Complications from these infections are serious, including death and long-term neurological injury and they are also costly to the health care system. For all of these reasons, hospitals began to develop protocols to reduce hospital-associated infections. For this study, we wanted to see how effective these efforts have been nationally in reducing these infections."
The study concluded that among the hospitals there was substantial decline in some infections during the investigation period. NICUs and PICUs both saw a 61 percent decline in central line-associated bloodstream infections. NICUs also saw a 50 percent reduction in ventilator-assisted pneumonias while PICUs rates dropped by 76 percent. Rates fell among neonates of all birth weights and among children.
Rates of catheter-associated urinary tract infections did not change significantly which could be attributed to variances in how CAUTIs are defined for surveillance purposes.
The study population included 174 hospitals reporting data to the Centers for Disease Control and Prevention for more than 5 million patient days, 1.2 million central line days and 380,000 ventilator days.
"For hospitals that participated in our study, we estimate that in addition to the harm that has been reduced there was approximately $131 million in savings of unnecessary health care expenditures," Patrick said.
Much of the changing tide over the years followed global calls for quality improvement efforts from concerned health organizations and systems. Nationally, a campaign called "Getting to zero" launched, while on the state level, the Tennessee Initiative for Perinatal Quality Care (TIPQC) was also implemented.
New policies and protocols were put into effect to reduce the unintended consequences of central lines and ventilators. Hospitals looked at various quality improvements including how and when lines were cleaned and used; if lines were necessary and for how long.
"This is a success story of multidisciplinary teams coming together to think, 'how do we make health care safer for America's children?' Our study shows these efforts appear to have been successful in reducing harm and saving millions of dollars for our health care system."
The study was supported by a grant from the Agency for Healthcare Research and Quality (R01HS018414-04).
This study was part of a collaborative effort between Vanderbilt University, Harvard Pilgrim Health Care, The Institute for Healthcare Improvement and the Centers for Medicare and Medicaid Services.
Craig Boerner | Eurek Alert!
Improving memory with magnets
28.03.2017 | McGill University
Graphene-based neural probes probe brain activity in high resolution
28.03.2017 | Graphene Flagship
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
28.03.2017 | Life Sciences
28.03.2017 | Information Technology
28.03.2017 | Physics and Astronomy