Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New study highlights potential for cost effective NHS policy

11.11.2008
A new University of Leicester study reveals that screening people who are at risk of developing diabetes could be a cost-effective health policy and improve the lives of patients.

In her inaugural lecture on Wednesday 12th November, Dr Clare Gillies of the Department of Health Sciences will reveal the results of her simulation study investigating the clinical and cost implications of screening people ‘at risk’ for impaired glucose intolerance and type 2 diabetes mellitus.

An important outcome of the work by Dr Gillies shows that early treatment and intervention resulting from this screening is potentially a cost-effective health policy for the UK.

Dr. Gillies is the winner of the School of Medicine Lauder Prize for best PhD. The prize will be awarded at the end of her lecture which starts at 5.30pm in the Frank and Katherine May lecture theatre, Henry Wellcome Building.

Her research involved comparing the cost and health implications of four different approaches to screening for impaired glucose tolerance and type 2 diabetes. These were:

i) no screening

ii) screening for type 2 diabetes alone resulting in health benefits from early diagnosis and treatment of the disease

iii) screening for impaired glucose tolerance and type 2 diabetes, allowing for both early treatment of diabetes and for lifestyle interventions to be applied to individuals with impaired glucose tolerance to reduce their risk of developing diabetes

iv) as for iii) but with pharmacological rather than lifestyle interventions

Dr Gillies developed a computer decision model using data from a number of sources to evaluate the cost and health implications of these four policies.

She said: “The model simulated a population with an increased risk of developing type 2 diabetes, who were aged 45 at the start of the model and thus time of screening. The model was run to estimate the cost and health implications over a 50 year time horizon, and the four different screening policies were then compared.

“Conclusions drawn from the work were that screening for type 2 diabetes and impaired glucose tolerance, with appropriate interventions for the latter, in an above average risk population at age 45, appears to be cost effective.

“The cost effectiveness of a policy of screening for diabetes alone, which offered no intervention to those with impaired glucose tolerance, is still uncertain and more information is needed on the long term health implications of early diagnosis and treatment of this disease.”

• The work was funded jointly by the Economic and Social Research Council (ESRC) and the Medical Research Council (MRC) as part of an interdisciplinary research initiative in the social and medical sciences.

Biography

Dr Clare Gillies is a medical statistician who has been based at the University of Leicester for 8 years, after gaining an MSc in medical statistics from the London School of Hygiene and Tropical Medicine in 2000. During this time she has worked on a number of projects including a Ph.D. investigating evidence synthesis methods for health policy decision making, with particular reference to policies concerning screening for type 2 diabetes mellitus. She joined the Ehleis project (European Health and Life Expectancy Information Systems) in 2007 and will be working on identifying factors associated with inequalities in healthy life years across EU member states, using a variety of datasets.

Dr. Clare Gillies is the winner of the School of Medicine Lauder Prize for best PhD. The prize will be awarded at the end of her lecture.

Ather Mirza | alfa
Further information:
http://www.leicester.ac.uk

More articles from Health and Medicine:

nachricht Investigators may unlock mystery of how staph cells dodge the body's immune system
22.09.2017 | Cedars-Sinai Medical Center

nachricht Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The pyrenoid is a carbon-fixing liquid droplet

Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.

A warming planet

Im Focus: Highly precise wiring in the Cerebral Cortex

Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.

The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Rainbow colors reveal cell history: Uncovering β-cell heterogeneity

22.09.2017 | Life Sciences

Penn first in world to treat patient with new radiation technology

22.09.2017 | Medical Engineering

Calculating quietness

22.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>