Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study Examines Lead Exposure and Accelerated Decline in Cognition in Older Women

31.03.2009
The April 2009 issue of the peer-reviewed journal Environmental Health Perspectives (EHP) reports on a study examining the association of chronic low-level exposure to lead and accelerated declines in cognition in women age 47–74 years.

Study findings suggest that cumulative exposure to lead at levels likely to be experienced in community settings may have adverse consequences for women’s cognition in their later years.

The objective of the study was to examine biomarkers of lead exposure in relation to performance on cognitive tests given to older women. Lead exposure is measured in two ways: blood lead level, which is a reading of recent lead dosage, and bone lead level, which is a cumulative measure of lead exposure over many years. For this study, the researchers assessed bone lead levels in the tibia and the patella.

The analysis of all cognitive tests combined showed levels of all three lead biomarkers were associated with worse cognitive performance, with the association between bone lead and letter fluency scoring dramatically different from the other bone lead/cognitive score associations. Although levels of patella and blood lead also were associated with worse cognitive function, results were statistically significant only for tibia lead, which typically reflects longer-ago exposures than patella lead. The pattern of association suggests that lead exposures in the distant past may be more important than relatively recent exposures in influencing cognitive function in older women.

“The identification of modifiable risk factors for cognitive decline may provide important clues for delaying or even preventing dementia,” wrote first author Jennifer Weuve and colleagues.

“Findings in this study are important because of their long-range consequences on the public health of an aging generation,” said EHP editor-in-chief Hugh A. Tilson, PhD. “Impaired cognition and cognitive decline in older women are associated with heightened risks of dementia, physical disability, hospitalization and reduced quality of life in later years.”

Other authors of the paper included Susan A. Korrick, Marc A. Weisskopf, Louise M. Ryan, Joel Schwartz, Huiling Nie, Francine Grodstein and Howard Hu. Support for this research was provided by the National Institute of Environmental Health Sciences, the National Cancer Institute, the National Institute on Aging and the National Institutes of Health.

The article is available free of charge at: http://www.ehponline.org/members/2008/11846/11846.html.

EHP is published by the National Institute of Environmental Health Sciences (NIEHS), part of the U.S. Department of Health and Human Services. EHP is an Open Access journal. More information is available online at http://www.ehponline.org/. Brogan & Partners Convergence Marketing handles marketing and public relations for the publication and is responsible for creation and distribution of this press release.

Julie Hayworth-Perman | Newswise Science News
Further information:
http://www.ehponline.org/

More articles from Health and Medicine:

nachricht 'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers
16.02.2018 | National University of Science and Technology MISIS

nachricht New process allows tailor-made malaria research
16.02.2018 | Eberhard Karls Universität Tübingen

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Contacting the molecular world through graphene nanoribbons

19.02.2018 | Materials Sciences

When Proteins Shake Hands

19.02.2018 | Materials Sciences

Cells communicate in a dynamic code

19.02.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>