Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study Examines Lead Exposure and Accelerated Decline in Cognition in Older Women

31.03.2009
The April 2009 issue of the peer-reviewed journal Environmental Health Perspectives (EHP) reports on a study examining the association of chronic low-level exposure to lead and accelerated declines in cognition in women age 47–74 years.

Study findings suggest that cumulative exposure to lead at levels likely to be experienced in community settings may have adverse consequences for women’s cognition in their later years.

The objective of the study was to examine biomarkers of lead exposure in relation to performance on cognitive tests given to older women. Lead exposure is measured in two ways: blood lead level, which is a reading of recent lead dosage, and bone lead level, which is a cumulative measure of lead exposure over many years. For this study, the researchers assessed bone lead levels in the tibia and the patella.

The analysis of all cognitive tests combined showed levels of all three lead biomarkers were associated with worse cognitive performance, with the association between bone lead and letter fluency scoring dramatically different from the other bone lead/cognitive score associations. Although levels of patella and blood lead also were associated with worse cognitive function, results were statistically significant only for tibia lead, which typically reflects longer-ago exposures than patella lead. The pattern of association suggests that lead exposures in the distant past may be more important than relatively recent exposures in influencing cognitive function in older women.

“The identification of modifiable risk factors for cognitive decline may provide important clues for delaying or even preventing dementia,” wrote first author Jennifer Weuve and colleagues.

“Findings in this study are important because of their long-range consequences on the public health of an aging generation,” said EHP editor-in-chief Hugh A. Tilson, PhD. “Impaired cognition and cognitive decline in older women are associated with heightened risks of dementia, physical disability, hospitalization and reduced quality of life in later years.”

Other authors of the paper included Susan A. Korrick, Marc A. Weisskopf, Louise M. Ryan, Joel Schwartz, Huiling Nie, Francine Grodstein and Howard Hu. Support for this research was provided by the National Institute of Environmental Health Sciences, the National Cancer Institute, the National Institute on Aging and the National Institutes of Health.

The article is available free of charge at: http://www.ehponline.org/members/2008/11846/11846.html.

EHP is published by the National Institute of Environmental Health Sciences (NIEHS), part of the U.S. Department of Health and Human Services. EHP is an Open Access journal. More information is available online at http://www.ehponline.org/. Brogan & Partners Convergence Marketing handles marketing and public relations for the publication and is responsible for creation and distribution of this press release.

Julie Hayworth-Perman | Newswise Science News
Further information:
http://www.ehponline.org/

More articles from Health and Medicine:

nachricht Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin

nachricht Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

Im Focus: Using graphene to create quantum bits

In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.

In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

Physicists discover mechanism behind granular capillary effect

24.05.2017 | Physics and Astronomy

Measured for the first time: Direction of light waves changed by quantum effect

24.05.2017 | Physics and Astronomy

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>