Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Size of hippocampus may indicate early dementia

16.11.2010
The size of the part of the brain known as the hippocampus may be linked to future dementia, reveals a thesis from the University of Gothenburg, Sweden.

Mild cognitive impairment, or MCI, is a condition where the cognitive functions are impaired – though not as severely as in dementia – and is a precursor to several types of dementia.

“One of the challenges for the healthcare is identifying which MCI patients have an underlying dementia disorder, which is why we need new tools to detect the early signs of dementia,” says Carl Eckerström, a researcher at the Sahlgrenska Academy’s Department of Psychiatry and Neurochemistry, and doctor at Sahlgrenska University Hospital’s memory clinic.

Atrophy of the hippocampus is common in Alzheimer’s disease. The thesis shows that the hippocampus may also be affected in small vessel disease (SIVD) which, along with Alzheimer’s, are the two most common types of dementia. SIVD is characterised by damage to the brain’s white matter and is considered to be the most important type of vascular dementia in the elderly.

Researchers measured the extent of changes to white matter in 122 MCI patients, and compared this with the size of their hippocampus. The patients were divided into two categories – one group who subsequently developed dementia after two years, and a second group whose clinical status remained unchanged after two years. There was also a group of healthy controls. The results showed that there may be a link between damage to the white matter and a reduction in the size of the hippocampus, which means that damage to the white matter could play a part in a process that leads to hippocampal atrophy.

“I believe that measuring the hippocampus could be a useful clinical instrument for investigating whether a person is in the early stages of dementia, as our findings suggest that the size of the hippocampus is linked to a deterioration in cognitive function and dementia,” says Eckerström.

THE HIPPOCAMPUS
The hippocampus is part of the limbic system and is located deep in the temporal lobe. It is vital for our ability to learn and is known as the brain’s memory centre. The hippocampus also helps with spatial awareness, enabling us to navigate our way around new places.
For more information, please contact:
Carl Eckerström, researcher at the Sahlgrenska Academy’s Department of Psychiatry and Neurochemistry, and doctor at Sahlgrenska University Hospital’s memory clinic, mobile: +46 (0)7 0440 0725, e-mail: Carl.eckerstrom@neuro.gu.se

Title of thesis: Hippocampal volumetry in mild cognitive impairment

Helena Aaberg | idw
Further information:
http://hdl.handle.net/2077/22902
http://www.gu.se

More articles from Health and Medicine:

nachricht Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena

nachricht Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>