Mild cognitive impairment, or MCI, is a condition where the cognitive functions are impaired – though not as severely as in dementia – and is a precursor to several types of dementia.
“One of the challenges for the healthcare is identifying which MCI patients have an underlying dementia disorder, which is why we need new tools to detect the early signs of dementia,” says Carl Eckerström, a researcher at the Sahlgrenska Academy’s Department of Psychiatry and Neurochemistry, and doctor at Sahlgrenska University Hospital’s memory clinic.
Atrophy of the hippocampus is common in Alzheimer’s disease. The thesis shows that the hippocampus may also be affected in small vessel disease (SIVD) which, along with Alzheimer’s, are the two most common types of dementia. SIVD is characterised by damage to the brain’s white matter and is considered to be the most important type of vascular dementia in the elderly.
Researchers measured the extent of changes to white matter in 122 MCI patients, and compared this with the size of their hippocampus. The patients were divided into two categories – one group who subsequently developed dementia after two years, and a second group whose clinical status remained unchanged after two years. There was also a group of healthy controls. The results showed that there may be a link between damage to the white matter and a reduction in the size of the hippocampus, which means that damage to the white matter could play a part in a process that leads to hippocampal atrophy.
“I believe that measuring the hippocampus could be a useful clinical instrument for investigating whether a person is in the early stages of dementia, as our findings suggest that the size of the hippocampus is linked to a deterioration in cognitive function and dementia,” says Eckerström.THE HIPPOCAMPUS
Title of thesis: Hippocampal volumetry in mild cognitive impairment
Advanced analysis of brain structure shape may track progression to Alzheimer's disease
26.10.2016 | Massachusetts General Hospital
Indian roadside refuse fires produce toxic rainbow
26.10.2016 | Duke University
Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.
This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
27.10.2016 | Materials Sciences
27.10.2016 | Physics and Astronomy
27.10.2016 | Life Sciences